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Aloe arborescens (Acemannan)

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HysteryDiagnosis Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Nov-25-10 12:07 PM
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Aloe arborescens (Acemannan)
A randomized study of chemotherapy versus biochemotherapy with chemotherapy plus Aloe arborescens in patients with metastatic cancer.
Lissoni P, Rovelli F, Brivio F, Zago R, Colciago M, Messina G, Mora A, Porro G.
Division of Radiation Oncology, St. Gerardo Hospital, Monza, Milan, Italy. [email protected]
Abstract

BACKGROUND: The recent advances in the analysis of tumor immunobiology suggest the possibility of biologically manipulating the efficacy and toxicity of cancer chemotherapy by endogenous or exogenous immunomodulating substances. Aloe is one of the of the most important plants exhibiting anticancer activity and its antineoplastic property is due to at least three different mechanisms, based on antiproliferative, immunostimulatory and antioxidant effects. The antiproliferative action is determined by anthracenic and antraquinonic molecules, while the immunostimulating activity is mainly due to acemannan.

PATIENTS AND METHODS: A study was planned to include 240 patients with metastatic solid tumor who were randomized to receive chemotherapy with or without Aloe. According to tumor histotype and clinical status, lung cancer patients were treated with cisplatin and etoposide or weekly vinorelbine, colorectal cancer patients received oxaliplatin plus 5-fluorouracil (5-FU), gastric cancer patients were treated with weekly 5-FU and pancreatic cancer patients received weekly gemcitabine. Aloe was given orally at 10 ml thrice/daily.

RESULTS: The percentage of both objective tumor regressions and disease control was significantly higher in patients concomitantly treated with Aloe than with chemotherapy alone, as well as the percent of 3-year survival patients.
CONCLUSION: This study seems to suggest that Aloe may be successfully associated with chemotherapy to increase its efficacy in terms of both tumor regression rate and survival time.
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Richard D Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Nov-25-10 12:10 PM
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1. A really common plant
That's been used by herbalists for a while to help treat cancer.
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Bobbieo Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Nov-25-10 01:30 PM
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2. So how do we utilize aloe for everday use - eat it, drink it or apply to skin?
I have tubs of aloe all over the yard.
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HysteryDiagnosis Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Nov-25-10 02:24 PM
Response to Reply #2
3. Aloe not prepared appropriately can lead to the common digestive
disorder known as diarrhea. If you do decide to produce your own, the inner leaf is where the magic is, some people cut this section into cubes and freeze it, taking one or two a day depending.

www.carringtonlabs.com has 10s of thousands of acres of organically grown aloe in Costa Rica that they harvest and use their proprietary freeze drying method to number one, separate out the acemannan, not an easy task, then dry it without breaking down the sugar... they produce various diabetic would care products for hospitals but they do offer "Manapol" in both pill form and liquid... their site is worth checking out.
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