New study identifies emergence of multidrug-resistant strain of salmonella

[OKIsItJustMe]

http://www.eurekalert.org/pub_releases/2011-08/idso-nsi080111.php

Public release date: 2-Aug-2011

Contact: John Heys
[email protected]
703-299-0412
http://www.idsociety.org/">Infectious Diseases Society of America

New study identifies emergence of multidrug-resistant strain of salmonella

A new study has identified the recent emergence of a multidrug-resistant strain of Salmonella that has a high level resistance to ciprofloxacin, a common treatment for severe Salmonella infections. The study, led by François-Xavier Weill, MD, and Simon Le Hello, PharmD, at the Pasteur Institute in France, is published in The Journal of Infectious Diseases and is now available online.

Salmonella infection represents a major public health problem worldwide. An estimated 1.7 million such infections occur in North America each year. More than 1.6 million cases were reported between 1999 and 2008 in 27 European countries. Although most Salmonella infections produce only mild gastroenteritis, elderly and immunocompromised patients are especially at risk for life-threatening infections. These cases are typically treated with antimicrobials called fluoroquinolones, such as ciprofloxacin.

Dr. Weill and colleagues studied information from national surveillance systems in France, England and Wales, Denmark, and the United States. The data showed that a multidrug-resistant strain of Salmonella, known as S. Kentucky, infected 489 patients in France, England and Wales, and Denmark between 2000 and 2008. In addition, researchers reported that the first infections were acquired mainly in Egypt between 2002 and 2005, while since 2006 the infections have also been acquired in various parts of Africa and the Middle East. The absence of reported international travel in approximately10 percent of the patients suggests that infections may have also occurred in Europe through consumption of contaminated imported foods or through secondary contaminations.

In this study, multidrug-resistant S. Kentucky was isolated from chickens and turkeys from Ethiopia, Morocco, and Nigeria, suggesting that poultry is an important agent for infection. The common use of fluoroquinolones in chicken and turkey production in Nigeria and Morocco may have contributed to this rapid spread.

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[Maine_Nurse]

1. Nowadays, it doesn't even take stupid antibiotic use...

to cause resistance, resistance factors can be conjugated from one bacterial species to another without our help at all. I'm gonna guess that these little critters will do a lot of us in. Mother Nature's smart bombs.

[sam11111]

2. Soviet Georgia (ex) uses bacteriophages that evolve in sewerage to eat any new MDR types

That is my vague memory of an NPR Peoples Pharmacy show.

Anyone know if that wd cure the OP problem?

Some Okla. Institute imports the phages.

[laconicsax]

3. Evolution in action. n/t