Retina Created from Human Embryonic Stem Cells

[IScreamSundays]

Source: Science Daily


It also marks the first step toward the development of transplant-ready retinas to treat eye disorders such as retinitis pigmentosa and macular degeneration that affect millions.

"We made a complex structure consisting of many cell types," said study leader Hans Keirstead of the Reeve-Irvine Research Center and the Sue and Bill Gross Stem Cell Research Center at UCI. "This is a major advance in our quest to treat retinal disease."

In previous studies on spinal cord injury, the Keirstead group originated a method by which human embryonic stem cells could be directed to become specific cell types, a process called differentiation. Results of those studies are leading to the world's first clinical trial using a stem cell-based therapy for acute spinal cord injury.

In this study, the Keirstead team utilized the differentiation technique to create the multiple cell types necessary for the retina. The greatest challenge, Keirstead said, was in the engineering. To mimic early stage retinal development, the researchers needed to build microscopic gradients for solutions in which to bathe the stem cells to initiate specific differentiation paths.

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Read more: http://www.sciencedaily.com/releases/2010/05/100526170248.htm

[leftynyc]

1. I have an uncle

with retinitis pigmentosa. We've watched his eyesight deteriorate for about a decade now. It's heartbreaking.

[sinkingfeeling]

2. Thanks for posting this.

[1monster]

3. Sending this off to my sister who lost all of what sight she had left because

her retina bleeding for years due to radiation treatments to treat retina blastoma in 1972..........

Thanks for posting!

[Curtis]

4. Awesome!

Just think how far along this sort of science we would be if Bush had allowed unfettered embryonic stem cell research

[FarLeftRage]

5. This is great news!

Maybe I can get the retina on my right eye replaced...
It was damaged to due laser surgery needed to cauterize enlarged blood vessels.