Reply #35: Not everyone who doubts Karr did it thinks Patsy did

[frogmarch]

Even many Ramsey supporters think he's the wrong guy. Determining this one way or the other will probably hinge on DNA.

Karr isn't the "engineer." He's a whacked-out, willing passenger.

According to molecular biologist Melissa Weber of CellMark Laboratories, the lab that did the DNA analysis on the samples found on the body, the so-called "foreign" DNA found on JonBenet's underpants (and under her fingernails) was degraded and had to be amplified through PCR amplification to obtain enough markers for comparison to samples of any suspects. During PCR amplification, damaged or old, degraded, imperfect DNA is amplified along with the good, and can give the false impression that another person's DNA is present, when it actually isn't. The two extra markers found in the "foreign" DNA sample could be merely stutter (also called shadow bands), a common problem occuring in PCR amplification, which often results in a false positive.

It has been theorized by law enforcement investigators and scientists alike that if the extra markers are actually from another person, that person could be someone who handled (or sneezed on) the underpants during their manufacture. The underpants were new, straight out of the package, and had not been washed prior to being found on the body.

If the markers from the amplified "foreign" DNA, erroneous though they may be, exactly match those in Karr's sample, they've probably got him.