Coronavirus: is this the next pandemic?
http://www.guardian.co.uk/science/2013/mar/15/coronavirus-next-global-pandemic
Professor Ali Mohamed Zaki, who diagnosed the first patient with a strain of the coronavirus in Saudi Arabia, stands in his office in Cairo. Photograph: David Degner/Getty Images
n mid-June last year, Ali Mohamed Zaki, a virologist at the Dr Soliman Fakeeh Hospital in Jeddah, Saudi Arabia, took a call from a doctor who was worried about a patient. The 60-year-old man had been admitted to the hospital with severe viral pneumonia and the doctor wanted Zaki to identify the virus. Zaki obtained sputum from the patient and set to work. He ran the usual lab tests. One after another they came back negative.
Puzzled by the results, Zaki sent a sample to a leading virology lab at Erasmus Medical Centre in Rotterdam. While he waited for the Dutch team to examine the virus, Zaki tried one more test of his own. This time he got a positive result. It showed the infectious agent belonged to a family of pathogens called coronaviruses. The common cold is caused by a coronavirus. So is the far more deadly infection Sars. Zaki quickly emailed the Dutch lab to raise the alarm. Their tests confirmed his fears, but went further: this was a coronavirus no one had seen before.
To alert other scientists, Zaki posted a note on proMED, an internet reporting system designed to rapidly share details of infectious diseases and outbreaks with researchers and public health agencies. The move cost him dearly. A week later, Zaki was back in his native Egypt, his contract at the hospital severed, he says, under pressure from the Saudi Arabian Ministry of Health. "They didn't like that this appeared on proMED. They forced the hospital to terminate my contract," Zaki told the Guardian from Cairo. "I was obliged to leave my work because of this, but it was my duty. This is a serious virus."
Just how serious was clear by then. While Zaki had worked to identify the virus, the patient's health had declined. His pneumonia worsened; his breath got shorter. His kidneys and other organs began to falter and fail. Despite all the drugs and dialysis, and mechanical ventilation to help him breathe, the man was dead 11 days after he arrived at the hospital