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HiPointDem

(20,729 posts)
Mon Sep 3, 2012, 02:03 AM Sep 2012

Genome Brings Ancient Girl to Life

In a stunning technical feat, an international team of scientists has sequenced the genome of an archaic Siberian girl 31 times over, using a new method that amplifies single strands of DNA. The sequencing is so complete that researchers have as sharp a picture of this ancient genome as they would of a living person’s, revealing, for example that the girl had brown eyes, hair, and skin...

That precision allows the team to compare the nuclear genome of this girl, who lived in Siberia’s Denisova Cave more than 50,000 years ago, directly to the genomes of living people, producing a “near-complete” catalog of the small number of genetic changes that make us different from the Denisovans, who were close relatives of Neandertals...

Meyer and his colleagues were able to detect for the first time that Denisovans, like modern humans, had 23 pairs of chromosomes, rather than 24 pairs, as in chimpanzees. By aligning the Denisovan genome with that of the reference human genome and counting mutations, the team calculated that the Denisovan and modern human populations finally split between 170,000 and 700,000 years ago...

http://www.wired.com/wiredscience/2012/08/denisovan-genome/

55 replies = new reply since forum marked as read
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Genome Brings Ancient Girl to Life (Original Post) HiPointDem Sep 2012 OP
That's impossible, HiPoint Jack Sprat Sep 2012 #1
Just ask rit momney. Coincidently that is also the last time he ........ left on green only Sep 2012 #3
Absolutely fascinating! CaliforniaPeggy Sep 2012 #2
God, I had to read that 3 times before I realized it didn't say Warren DeMontague Sep 2012 #4
magic! HiPointDem Sep 2012 #5
Anyway Warren DeMontague Sep 2012 #7
It was G. Gnome. n/t lumberjack_jeff Sep 2012 #48
It was obviously post-migratory when different species of human existed side by side... Spitfire of ATJ Sep 2012 #6
Aw-w, ni-i-ice! "Norton blocked an attack . . . " when I clicked on that link! Petrushka Sep 2012 #8
Norton is notoriously overzealous in it's paranoia... Spitfire of ATJ Sep 2012 #9
Seriously, I appreciate such overzealousness.. Petrushka Sep 2012 #10
"After a while, it ceased to be funny." Spitfire of ATJ Sep 2012 #11
I never thought making fun of poor people for their weight & clothes was funny in the first place. HiPointDem Sep 2012 #12
True, but a lot of these people are going to vote Republican... Spitfire of ATJ Sep 2012 #13
there's no connection between the two; and poor people lean democrat, not republican. HiPointDem Sep 2012 #14
Uh huh,...sure... Spitfire of ATJ Sep 2012 #15
SOME poor people lean Democrat, but many more might lean Republican . . . Petrushka Sep 2012 #18
People making under $30K were the ONLY income group to go Democrat in the last election (2010). HiPointDem Sep 2012 #25
Good comedy makes fun of everyone... Mmm_Bacon Sep 2012 #16
there's nothing funny about making fun of the powerless. that's why conservative humor sucks. HiPointDem Sep 2012 #23
Just the subjects you find comfortable with then.... Mmm_Bacon Sep 2012 #26
a world where people don't pick on the weak doesn't sound boring to me. HiPointDem Sep 2012 #27
+1 eom chknltl Sep 2012 #55
I guess the woman in the pic is powerless to dress just slightly kestrel91316 Sep 2012 #30
'skanky' is your judgment of her outfit. HiPointDem Sep 2012 #36
No. Many women could wear that and not look bad. She's not one of them. kestrel91316 Sep 2012 #42
skanky = slutty. a character judgment based on her outfit. your judgment. HiPointDem Sep 2012 #43
Willy the Wal-Mart Pimp still gets a chuckle Scootaloo Sep 2012 #17
i don't see anything funny about it. a man wearing an unusual outfit. why is that funny? HiPointDem Sep 2012 #24
Context Scootaloo Sep 2012 #33
the context is people looking at pictures of funny-looking people on a website dedicated to HiPointDem Sep 2012 #35
I actually gotta respect that Posteritatis Sep 2012 #32
Willy got nothin' on Mitt the Shit. Mitt is the ultimate Wal Mart pimp. Kurovski Sep 2012 #50
I agree. I despise Walmart; but, making fun of the poor people who shop there is a low blow! LongTomH Sep 2012 #44
well, the white woman with the swastika shirt and the black boyfriend is funny arely staircase Sep 2012 #46
Not only do we have to violate the privacy of folks alive today, Trillo Sep 2012 #19
What in God's name does German paleoanthropology have to do with the Fourth Amendment? Posteritatis Sep 2012 #31
DNA is behind the "locked door" of a cell wall. Trillo Sep 2012 #34
*facepalm* (nt) Posteritatis Sep 2012 #37
You must not be a democrat, Trillo Sep 2012 #39
I doubt that a 50,000 year-old non-human Siberian hominid is covered by the 4th amendment. lumberjack_jeff Sep 2012 #49
The Fourth Amendment has NOTHING to do with an ancient Siberian girl csziggy Sep 2012 #53
How long before someone tries to clone her? HopeHoops Sep 2012 #20
That was my first thought when I read that headline! (eom) Petrushka Sep 2012 #21
They're trying to use an elephant to bring back the mammoth (as a zoo object). HopeHoops Sep 2012 #22
Probably not to long... Kalidurga Sep 2012 #29
Ah, yes, I remember Dolly. HopeHoops Sep 2012 #47
Soon WhoIsNumberNone Sep 2012 #40
I interpreted it that the sample was effectively incomplete so a clone wouldn't be possible. davepdx Sep 2012 #41
There's a Syfy channel movie in this!!!! LongTomH Sep 2012 #45
Oh great now we have to keep up with the Denisovans n/t flamingdem Sep 2012 #28
DUzy! Kurovski Sep 2012 #52
Thanks for the props! flamingdem Sep 2012 #54
Maybe they could clone her WhoIsNumberNone Sep 2012 #38
That's fascinating! JustAnotherGen Sep 2012 #51

left on green only

(1,484 posts)
3. Just ask rit momney. Coincidently that is also the last time he ........
Mon Sep 3, 2012, 02:13 AM
Sep 2012

changed his magic underwear, me thinks.

CaliforniaPeggy

(149,907 posts)
2. Absolutely fascinating!
Mon Sep 3, 2012, 02:12 AM
Sep 2012

I think genetics is one of the most interesting fields these days.

Thanks for posting this.

 

Spitfire of ATJ

(32,723 posts)
6. It was obviously post-migratory when different species of human existed side by side...
Mon Sep 3, 2012, 05:09 AM
Sep 2012

...there's evidence they bred with each other and passed on traits to their decedents.

Ever go to this site?

http://www.peopleofwalmart.com/

My fav:

[img][/img]

Petrushka

(3,709 posts)
10. Seriously, I appreciate such overzealousness..
Mon Sep 3, 2012, 06:24 AM
Sep 2012

Especially after losing four years worth of work and research to a virus way-back-when.



P.S.
I followed that Walmart People website when it was still in its infancy. After a while, it ceased to be funny.

 

HiPointDem

(20,729 posts)
12. I never thought making fun of poor people for their weight & clothes was funny in the first place.
Mon Sep 3, 2012, 06:34 AM
Sep 2012

Good comedy makes fun of the powerful and arrogant.

Humor that targets the powerless and weak isn't funny, anymore than a bully who picks on people smaller than him is funny.

 

Spitfire of ATJ

(32,723 posts)
13. True, but a lot of these people are going to vote Republican...
Mon Sep 3, 2012, 06:48 AM
Sep 2012

...the same way people used to volunteer to be a sacrifice to a volcano.

 

HiPointDem

(20,729 posts)
14. there's no connection between the two; and poor people lean democrat, not republican.
Mon Sep 3, 2012, 06:51 AM
Sep 2012

it's really counterproductive of democrats to make fun of low-income people, in fact.

but they do it all the time, and make assumptions like you just did.

 

Spitfire of ATJ

(32,723 posts)
15. Uh huh,...sure...
Mon Sep 3, 2012, 07:00 AM
Sep 2012

Obviously you are unaware of the mindset of some of these people.

They HAVE to vote Republican to stop the "Democrats".

Classic "low information voters".

Petrushka

(3,709 posts)
18. SOME poor people lean Democrat, but many more might lean Republican . . .
Mon Sep 3, 2012, 09:33 AM
Sep 2012

. . . otherwise Obama would have carried my home-state, West Virginia---and ex-Congressman Mollohan would have carried the state's first district!

Also: In fact: Making fun of people isn't the same thing as finding some people's antics funny, regardless of their income status. I mean: If someone chooses to run around anywhere in public with all of his or her goodies hanging out in a display that silently shouts "Up yours!" at those who take offense, I might not laugh at them but you can be sure I'll shake my head in wonderment and try not to smile. I would never, however, stop to ask them their party affiliation or the level of their income.

 

HiPointDem

(20,729 posts)
25. People making under $30K were the ONLY income group to go Democrat in the last election (2010).
Mon Sep 3, 2012, 12:53 PM
Sep 2012

With the 2010 midterms come and gone, one question we at OOTS asked is how low-income Americans voted.

According to CNN’s national exit polling, the lowest income bracket, those making under $30,000 a year, voted 56 percent Democrat compared to 41 percent Republican.

This gap closes in the next income bracket, between $30,000 and $50,000, in which voters prefer Democrats over Republicans by a margin of 51 percent to 46 percent.

It’s worth noting that in this election only those earning less than $50,000 voted in the majority for Democrats. Above the $50,000 income line, voters swung Republican.

http://www.spotlightonpoverty.org/OutOfTheSpotlight.aspx?id=f733d09b-6808-4115-9b88-8c89262c7b3d


People who make fun of low-income people for their personal appearance do so because of their own status anxieties.

People who go on about how low-income people "vote against their own interest" are ill-informed, as low-income people are the group *most* likely to vote for democrats.

the problem is not that low-income folks are liable to vote republican, but that they are less likely to vote, period. mostly because they've figured that voting won't change their personal situation. and they're pretty much correct in that these days.

 

HiPointDem

(20,729 posts)
23. there's nothing funny about making fun of the powerless. that's why conservative humor sucks.
Mon Sep 3, 2012, 12:28 PM
Sep 2012

like dennis miller.

you're mistaken, my friend.

 

Scootaloo

(25,699 posts)
33. Context
Mon Sep 3, 2012, 02:29 PM
Sep 2012

You're plodding through Wal-Mart. You round an aisle, and standing there is a man in pink pinstripes, wearing a feathered hat and gold silk scarves. You look at him. he looks at you - through star-shaped sunglasses.

"Sup?" he asks, as if this were just another day, anywhere else. Because, for him, it is.

Your day is probably a little different now. perhaps not what you were expecting.

 

HiPointDem

(20,729 posts)
35. the context is people looking at pictures of funny-looking people on a website dedicated to
Mon Sep 3, 2012, 02:40 PM
Sep 2012

making fun of funny-looking people who shop at walmart.

Posteritatis

(18,807 posts)
32. I actually gotta respect that
Mon Sep 3, 2012, 02:01 PM
Sep 2012

Especially speaking as someone who's rather more selfconscious than I want to be.

That's someone who's comfortable in his own skin.

LongTomH

(8,636 posts)
44. I agree. I despise Walmart; but, making fun of the poor people who shop there is a low blow!
Mon Sep 3, 2012, 04:34 PM
Sep 2012

Many of those people don't have any choice. Either they can't afford to shop anywhere else, or Wally World has driven all the local shops in their area out of business.

Trillo

(9,154 posts)
19. Not only do we have to violate the privacy of folks alive today,
Mon Sep 3, 2012, 09:53 AM
Sep 2012

we also refuse to let the dead rest in peace, and we have to violate their privacy, as well. Thank goodness they're dead, it would seem rather difficult for them to either be aware of or care about the gravesite violation. Us, on the other hand ... Why forcibly teach us as kids we have a 4th Amendment, if it's clear to most of us as adults, we do not.

Posteritatis

(18,807 posts)
31. What in God's name does German paleoanthropology have to do with the Fourth Amendment?
Mon Sep 3, 2012, 01:44 PM
Sep 2012

Gah, that's the most absurd kneejerk I've seen around here in... well, hours.

Trillo

(9,154 posts)
34. DNA is behind the "locked door" of a cell wall.
Mon Sep 3, 2012, 02:40 PM
Sep 2012

Sure, it may be dissolved, but with the right chemicals, so may your front door. 4th Amendment protects personal papers and effects against search and seizure. DNA are basically instructions, the blueprint if you will, of the organism. It doesn't get any more personal than that.

Your insults are noted. I shall refrain from insulting you. Please pass that kindness on to the next person you disagree with.

Trillo

(9,154 posts)
39. You must not be a democrat,
Mon Sep 3, 2012, 02:45 PM
Sep 2012

for you sure can't stop the insults, even when asked politely. If your intent is to get people to switch to third party, or to republicans (barf) yours is a superior strategery.

 

lumberjack_jeff

(33,224 posts)
49. I doubt that a 50,000 year-old non-human Siberian hominid is covered by the 4th amendment.
Tue Sep 4, 2012, 10:42 AM
Sep 2012

Genes or otherwise.

csziggy

(34,141 posts)
53. The Fourth Amendment has NOTHING to do with an ancient Siberian girl
Tue Sep 4, 2012, 11:45 AM
Sep 2012

Or the German paleoanthropolists who sampled her DNA.

I'm not sure why you would think any portion of the American Constitution would be binding to people in other countries.

As for "gravesite violation" - there was no gravesite. All that remains of this girl are one tiny finger bone and two teeth. It is amazing that they were found at all and remarkable that they were even recognized as human.

Frankly, if this person were one of my distant relatives, I would not have any objection to scientists digging her up and investigating her remains in order to gain more information about human origins. The knowledge gained could benefit future generations.

 

HopeHoops

(47,675 posts)
22. They're trying to use an elephant to bring back the mammoth (as a zoo object).
Mon Sep 3, 2012, 11:57 AM
Sep 2012

How do you think a girl brought back from the same technique would feel in a world like ours? Obviously she wouldn't have any memory of her previous life, but she'd be treated as a freak to be studied. I have no problem with the study of DNA differences, but DO NOT FUCK WITH THEM!

davepdx

(224 posts)
41. I interpreted it that the sample was effectively incomplete so a clone wouldn't be possible.
Mon Sep 3, 2012, 02:50 PM
Sep 2012

From the article:

"The team was able to cover 99.9 percent of the mappable nucleotide positions in the genome at least once, and more than 92 percent of the sites at least 20 times, which is considered a benchmark for identifying sites reliably."

Edited to add: I could be wrong.

LongTomH

(8,636 posts)
45. There's a Syfy channel movie in this!!!!
Mon Sep 3, 2012, 04:38 PM
Sep 2012

They could have the cloned girl fall in love with one of the scientists cloning her. It would be a hopeless, poignant story. Unfortunately, Syfy would just turn it into a 'kill the monster' horror feature.

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