Eating too much packs on more fat for diabetics' kin
Overeating is more fattening for people who have a close relative with diabetes, a study found.
Adults who have at least one immediate relative with type-2 diabetes and who consumed 1,250 calories more than required daily gained 55 percent more weight than those without the close ties.
Overfeeding induced resistance to insulin, the hormone used to convert blood sugar to energy, and liver-fat deposition in both groups, said researchers at Australia's Garvan Institute. The increase in fat was closely aligned with the amount of weight gained, they said.
"Our study shows just how quickly the body reacts to overeating, and how harmful it can be in susceptible people," said study co-author Lesley Campbell. "While we expected differences between the two groups, we were surprised by the amount of extra weight the diabetes-prone group gained."
The researchers set out to mimic the kind of overeating that typically takes place during feasting periods, such as between Thanksgiving and New Year. They compared the effects of 28 days of overfeeding on 17 adults with a family history of type-2 diabetes against 24 who had no known genetic predisposition to the disease.
http://www.dispatch.com/live/content/national_world/stories/2010/05/12/eating-too-much-packs-on-more-fat-for-diabetics-kin.html?sid=101