Democratic Underground Latest Greatest Lobby Journals Search Options Help Login

What was the FDA thinking?

Printer-friendly format Printer-friendly format
Printer-friendly format Email this thread to a friend
Printer-friendly format Bookmark this thread
Home » Discuss » DU Groups » Health & Disability » Cancer Support Group Donate to DU
bluescribbler Donating Member (1000+ posts) Send PM | Profile | Ignore Wed May-06-09 10:46 AM
Original message
What was the FDA thinking?
Wife met with the oncologist yesterday. She had been in a clinical trial for a monoclonal antibody, MDX anti CTLA-4, for 2 1/2 years, but dropped out last year. Her reasoning was that her lung and breast mets were growing slowly, basically at the same rate as before she started the trial, increasing side fx, the rigamarole of frequent hospital visits and blood tests, (all required by the trial), and the docotor's opinion that the drug would soon be approved by the FDA, and she would be able to get it in a much simpler setting.

Unfortunately, since she dropped out of the trial, she has had mets to her brain. Perhaps she was getting some benefit from the drug, after all.

So she asked him about the drug's progress through the FDA approval bureaucracy. He said that it will likely be approved before fall, but here's the kicker. It will be approved for use with chemotherapy. The drug has been tested on approximately 8000 patients, none of whom were doing concurrent chemo, so noone has the slightest idea how the drugs will interact, but the FDA is saying, if you want CTLA-4, you have to do chemo as well. :mad: Doc says it's bad science, and I totally agree. :wtf:
Refresh | 0 Recommendations Printer Friendly | Permalink | Reply | Top
LeighAnn Donating Member (1000+ posts) Send PM | Profile | Ignore Sat May-16-09 10:33 PM
Response to Original message
1. Yep. I hate that
That's a shame when bureaucrats tie the hands of physicians who know better.

I hope your wife is doing okay, and that her oncology team can find something else effective.

Printer Friendly | Permalink | Reply | Top
Forkboy Donating Member (1000+ posts) Send PM | Profile | Ignore Sun May-17-09 03:05 AM
Response to Original message
2. That's just sucky.
I'm sorry, man. That's not right at all. :(

Best wishes to your wife.
Printer Friendly | Permalink | Reply | Top
DU AdBot (1000+ posts) Click to send private message to this author Click to view 
this author's profile Click to add 
this author to your buddy list Click to add 
this author to your Ignore list Fri Sep 22nd 2017, 11:10 PM
Response to Original message
Advertisements [?]

Home » Discuss » DU Groups » Health & Disability » Cancer Support Group Donate to DU

Powered by DCForum+ Version 1.1 Copyright 1997-2002
Software has been extensively modified by the DU administrators

Important Notices: By participating on this discussion board, visitors agree to abide by the rules outlined on our Rules page. Messages posted on the Democratic Underground Discussion Forums are the opinions of the individuals who post them, and do not necessarily represent the opinions of Democratic Underground, LLC.

Home  |  Discussion Forums  |  Journals |  Store  |  Donate

About DU  |  Contact Us  |  Privacy Policy

Got a message for Democratic Underground? Click here to send us a message.

© 2001 - 2011 Democratic Underground, LLC