Vaccines with the MF59 Adjuvant Do Not Stimulate Antibody Responses against Squalene

[HuckleB]

Yeah, it's not a brand new study, but it covers a topic of "new" hysteria on the board.


http://www.vaccines.mil/documents/library/MF59.pdf

"Squalene is a naturally occurring oil which has been used in the development of vaccine adjuvants, such as
the oil-in-water emulsion MF59. In past years, by use of noncontrolled and nonvalidated assays, a claim was
made that antisqualene antibodies were detectable in the sera of individuals with the so-called Gulf War
syndrome. Using a validated enzyme-linked immunosorbent assay for the quantitation of immunoglobulin G
(IgG) and IgM antibodies against squalene, we demonstrated that antisqualene antibodies are frequently
detectable at very low titers in the sera of subjects who were never immunized with vaccines containing
squalene. More importantly, vaccination with a subunit influenza vaccine with the MF59 adjuvant neither
induced antisqualene antibodies nor enhanced preexisting antisqualene antibody titers. In conclusion, antisqualene
antibodies are not increased by immunization with vaccines with the MF59 adjuvant. These data
extend the safety profile of the MF59 emulsion adjuvant."

---------------------------------------------------------------------------------------------------------------------------

More on the matter:


Study on the safety and immunogenicity of MF59-adjuvanted influenza subunit vaccine in Chinese elderly
http://www.ncbi.nlm.nih.gov/pubmed/19040034

Safety and immunogenicity of MF59-adjuvanted influenza vaccine in the elderly
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TD4-3X115S9-N&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&_docanchor=&view=c&_searchStrId=1038702152&_rerunOrigin=google&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=d4919d40a4d3bd83143c024700653f7c

A Phase II, randomized, controlled, observer-blind, single-center study to evaluate the immunogenicity,
safety and tolerability of two doses of MF59®-adjuvanted H5N1 influenza vaccine, AFLUNOV®, in
subjects aged 6 months to 17 years
http://www.who.int/vaccine_research/immunogenicity/82_astractvisicari.pdf

[SidDithers]

1. But these aren't links to whale.to, mercola or globalresearch...

so they're obviously either government propaganda, or bought and paid for by Big Pharma.

Sid

[HuckleB]

2. You got me there!

[uppityperson]

3. thank you. k&r

[sheldon101]

4. Blame Canada.

AS I will be discussing adjuvants, Big Pharma requires me to state the following:

1. None of the flu vaccines approved for use in the United States contain any adjuvant, any squalene or any alum.

2. There are no plans to add an adjuvant to any vaccine for this flu season.

3. If an adjuvant is added, no one will complain because that means demand has spiked higher than supply. You go from 15mcg of viral stuff per dose to 5.25 mcg or 3.75 mcg(Canada). That means the prevalent virus is much nastier and as expected the vaccine still is very effective.

4. The US is carrying out small scale trials using flu vaccine plus adjuvant,(against H1N1 and the seasonal flu) looking for a stronger immune response in the elderly which would make the seasonal flu shot more effective.
--------------------- end of forced Big Pharma messge

Practically all Canadians will be vaccinated with 3.75mcg of viral material plus the AS03 adjuvant. By a remarkable coincidence the US bought large stocks of AS03, it case it was needed.Come next spring, the safety profile of AS03 will be stronger thanks to the Canadians. Proof of the safety of the adjuvant in Canada will make it easier to introduce in the US.

Thus bringing closer to date the destruction of the world by the anti-Christ and his friend Bob.

Blame Canada.

zz66eeaa99ww123

[snagglepuss]

7. interesting info

[xchrom]

5. kick

[mzmolly]

6. KnR. I'm much more concerned about aluminum and it's

potential link to GWI, personally.