Cataracts.... not necessary after all.... reversal possible with simple

[HysteryDiagnosis]

nutrient based drops. True story.

http://www.clubnatural.com/canceye.html

While Santa Lucia eye-drops remove toxins, the NAC drops, well researched and documented for over 10 years, put something “into” the eye—a special form of the amino acid carnosine, called n-alpha-acetyl-carnosine** (pronounced -a seat till car no seen) in a synergistic lubricant formula. Effects are like “melting snow” as cataract reversal starts from the edges and the lens becomes more transparent.

**Please note: N-alpha-acetylcarnosine is carnosine in its purest form. Also known as N-acetylcarnosine and abbreviated *NAC, it is not to be confused with N-acetylcysteine, another amino acid which sometimes shares the same abbreviation.

[trotsky]

1. Wow! Amazing!

I assume there are links to the peer-reviewed studies that have been done to prove this product's effectiveness?

[HysteryDiagnosis]

7. Actually, I'm glad you asked... I was fishing for a doc to make a

case that this is a sales site, yada yada yada..... so here you go.

This is NOT copyrighted mods...

1: Rejuvenation Res. 2004 Fall;7(3):186-98. Related Articles, Links


Rejuvenation of visual functions in older adult drivers and drivers with cataract during a short-term administration of N-acetylcarnosine lubricant eye drops.

Babizhayev MA.

Innovative Vision Products, Inc. Moscow Division, Ivanovskaya 20, Suite 74, Moscow 127434, Russian Federation. [email protected]

The purpose of this study was to examine using the original halometer glare test of the type of visual impairment mediated by the increased glare sensitivity (halos) and associated with poorer visual function in both the better and worse eyes of older adult drivers and older drivers with cataract. The clinically validated (by Innovative Vision Products Inc.) formula of 1% N-acetylcarnosine (NAC) lubricant eye drops were applied topically to the eyes of older drivers to reduce glare disability and improve distance acuities for driving. This was a randomized, double-blind, placebo-controlled study. The examined subjects consisted of 65 older adults with cataract in one or both eyes, and 72 adult drivers who did not have cataract in either eye. In the control group, comparison with baseline values showed some variability of data in gradual worsening of glare sensitivity at red and green targets and minimal VA changes over 4 months. In the NAC-treated group, 4-month follow-up generally showed an improvement in VA and a significant improvement in glare sensitivity at red and green targets was documented in worse and better eyes using a critical cut point halometer score for driving. The NAC-treated eyes had statistically significant difference in VA, glare sensitivity compared with the control group ( p < 0.001) at 4-month timepoint of treatment, as supported by the overall t-test results of the ratio of the follow-up data to the baseline values. Tolerability of NAC eyedrops was good in almost all patients, with no reports of ocular or systemic adverse effects. It would be advisable for traffic safety if a Halometer glare sensitivity test was implemented for vehicles and/or was regularly added to the requirements for a driver's licence. The results of this study provide a substantial basis for further evaluation of NAC in the treatment and prevention of vision impairment in the older population of drivers for legal driving. The developed ophthalmic drug NAC formula showed potential for the non-surgical treatment of age-related cataracts.

Publication Types:
Clinical Trial
Randomized Controlled Trial

PMID: 15588519


1: Drugs R D. 2002;3(2):87-103. Related Articles, Links


Efficacy of N-acetylcarnosine in the treatment of cataracts.

Babizhayev MA, Deyev AI, Yermakova VN, Semiletov YA, Davydova NG, Doroshenko VS, Zhukotskii AV, Goldman IM.

Innovative Vision Products, Inc., County of Newcastle, Delaware, USA. [email protected]

PURPOSE: To evaluate the effects of 1% N-acetylcarnosine (NAC) solution on lens clarity over 6 and 24 months in patients with cataracts. TRIAL DESIGN: Randomised, placebo-controlled study. PARTICIPANTS: 49 subjects (76 affected eyes) with an average age of 65.3 +/- 7.0 years with a diagnosis of senile cataract with minimum to advanced opacification in various lens layers. METHODS: 26 patients (41 eyes) were allocated to topical NAC 1% eyedrops twice daily. The control group consisted of 13 patients (21 eyes) who received placebo eyedrops and 10 patients (14 eyes) who did not receive eyedrops. MAIN OUTCOME MEASURES: All patients were evaluated at entry and followed up every 2 months for a 6-month period (trial 1), or at 6-month intervals for a 2-year period (trial 2), for best-corrected visual acuity and glare testing. In addition, cataract was measured using stereocinematographic slit-images and retro-illumination examination of the lens. Digital analysis of lens images displayed light scattering and absorbing centres in two- and three-dimensional scales. RESULTS: The overall intra-reader reproducibility of cataract measurements (image analysis) was 0.830, and glare testing 0.998. After 6 months, 90% of NAC-treated eyes showed improvement in best corrected visual acuity (7 to 100%) and 88.9% showed a 27 to 100% improvement in glare sensitivity. Topographic studies indicated fewer areas of posterior subcapsular lens opacity and 41.5% of treated eyes had improvement in image analysis characteristics. The overall ratios of image analysis characteristics at 6 months compared with baseline measures were 1.04 and 0.86 for the control and NAC-treated group, respectively (p < 0.001). The apparent benefits of treatment were sustained after 24 months' treatment. No treated eyes demonstrated worsening of vision. The overall visual outcome in the control group showed significant worsening after 24 months in comparison with both baseline and the 6-month follow-up examination. The overall clinical results observed in the NAC-treated group by the 24-month period of examination differed significantly (p < 0.001) from the control group in the eyes with cortical, posterior subcapsular, nuclear or combined lens opacities. Tolerability of NAC eyedrops was good in almost all patients, with no reports of ocular or systemic adverse effects. CONCLUSION: Topical NAC shows potential for the treatment and prevention of cataracts.

Publication Types:
Clinical Trial
Randomized Controlled Trial

PMID: 12001824

1: Babizhayev MA. Links
Biological activities of the natural imidazole-containing peptidomimetics n-acetylcarnosine, carcinine and l-carnosine in ophthalmic and skin care products.
Life Sci. 2005 Dec 29;
PMID: 16388826

2: Related Articles, Links

Biomed Khim. 2005 Sep-Oct;51(5):481-4. Russian.
PMID: 16342664

3: Babizhayev MA. Related Articles, Links
Analysis of lipid peroxidation and electron microscopic survey of maturation stages during human cataractogenesis: pharmacokinetic assay of Can-C N-acetylcarnosine prodrug lubricant eye drops for cataract prevention.
Drugs R D. 2005;6(6):345-69.
PMID: 16274259

4: Babizhayev MA. Related Articles, Links
Rejuvenation of visual functions in older adult drivers and drivers with cataract during a short-term administration of N-acetylcarnosine lubricant eye drops.
Rejuvenation Res. 2004 Fall;7(3):186-98.
PMID: 15588519

5: Babizhayev MA, Deyev AI, Yermakova VN, Brikman IV, Bours J. Related Articles, Links
Lipid peroxidation and cataracts: N-acetylcarnosine as a therapeutic tool to manage age-related cataracts in human and in canine eyes.
Drugs R D. 2004;5(3):125-39. Review.
PMID: 15139774

6: Babizhayev MA, Deyev AI, Yermakova VN, Semiletov YA, Davydova NG, Doroshenko VS, Zhukotskii AV, Goldman IM. Related Articles, Links
Efficacy of N-acetylcarnosine in the treatment of cataracts.
Drugs R D. 2002;3(2):87-103.
PMID: 12001824

7: Babizhayev MA, Deyev AI, Yermakova VN, Semiletov YA, Davydova NG, Kurysheva NI, Zhukotskii AV, Goldman IM. Related Articles, Links
N-Acetylcarnosine, a natural histidine-containing dipeptide, as a potent ophthalmic drug in treatment of human cataracts.
Peptides. 2001 Jun;22(6):979-94.
PMID: 11390029

8: Babizhayev MA, Yermakova VN, Semiletov YA, Deyev AI. Related Articles, Links
The natural histidine-containing dipeptide Nalpha-acetylcarnosine as an antioxidant for ophthalmic use.
Biochemistry (Mosc). 2000 May;65(5):588-98.
PMID: 10851037

9: Quinn PJ, Boldyrev AA, Formazuyk VE. Related Articles, Links
Carnosine: its properties, functions and potential therapeutic applications.
Mol Aspects Med. 1992;13(5):379-444. Review.
PMID: 9765790

10: Babizhayev MA, Yermakova VN, Sakina NL, Evstigneeva RP, Rozhkova EA, Zheltukhina GA. Related Articles, Links
N alpha-acetylcarnosine is a prodrug of L-carnosine in ophthalmic application as antioxidant.
Clin Chim Acta. 1996 Oct 15;254(1):1-21. Erratum in: Clin Chim Acta 1997 Mar 18;259(1-2):199-201.
PMID: 8894306

11: Babizhayev MA. Related Articles, Links
Failure to withstand oxidative stress induced by phospholipid hydroperoxides as a possible cause of the lens opacities in systemic diseases and ageing.
Biochim Biophys Acta. 1996 Mar 1;1315(2):87-99.
PMID: 8608175

12: Babizhayev MA, Costa EB. Related Articles, Links
Lipid peroxide and reactive oxygen species generating systems of the crystalline lens.
Biochim Biophys Acta. 1994 Feb 22;1225(3):326-37.
PMID: 8312381

13: Formaziuk VE, Sergienko VI. Related Articles, Links

Biokhimiia. 1992 Sep;57(9):1404-16. Review. Russian.
PMID: 1334708

14: Formaziuk VE, Dudina EI, Sergienko VI. Related Articles, Links

Biull Eksp Biol Med. 1992 Feb;113(2):159-61. Russian.
PMID: 1611063

15: Chasovnikova LV, Formaziuk VE, Sergienko VI, Belikova TV, Vladimirov IuA. Related Articles, Links

Biofizika. 1991 Jul-Aug;36(4):648-51. Russian.
PMID: 1793749

16: Chasovnikova LV, Formazyuk VE, Sergienko VI, Boldyrev AA, Severin SE. Related Articles, Links
The antioxidative properties of carnosine and other drugs.
Biochem Int. 1990;20(6):1097-103.
PMID: 2369412

17: Babizhayev MA. Related Articles, Links
Antioxidant activity of L-carnosine, a natural histidine-containing dipeptide in crystalline lens.
Biochim Biophys Acta. 1989 Aug 22;1004(3):363-71.
PMID: 2758030

18: Boldyrev AA, Dupin AM, Bunin AYa, Babizhaev MA, Severin SE. Related Articles, Links
The antioxidative properties of carnosine, a natural histidine containing dipeptide.
Biochem Int. 1987 Dec;15(6):1105-13. Review.
PMID: 3326603

[Caution]

11. You have made your case completely

A study created, proposed by, run by and finally peer reviewed by the actual manufacturer of said cure. Yep. good science there.

Clearly a case that this is a sales site.

It actually is pretty funny that the alternative medicine community is using the same tactics that the Inetlligent Design folks use. I love the constant attacks on the science of the reputable medical community myself. That's my favorite. The playing off on people's mistrust of authority. The use of utterly meaningless buzzwords like "toxin" The misrepresentation of a single, self-funded self-run "study" that proves the effectiveness. The use of customer testimonials. The use of their own customers as sales agents. The creation of "medical" degrees granted by institutions that were founded by those who received the "degrees." The appeal to the conservative side in all of us regarding the "ancient" methods used for "millenia" but hidden from us by the meical community who "don't want you to know about the miracle cures used in the far east every day!"

It would be funny as hell if it weren't for the fact that people can actually harm themselves by using unregulated, untested, medical treatments without the advice of their doctor, without understanding that these therapies can have very nasty side effects when used in combination with other therapies without consulting an actual qualified medical doctor first. You want to use this stuff? Fine. But consult a doctor first. a REAL doctor. One with an MD. And don't try to push therapies on people without advising them to do the same. You could be the one who causes someone to die from an allergic reaction or from a bad combination of substances that causes horrific side effects.

Maybe this substance works. I seriously doubt it because cataracts are scar tissue and if this stuff could remove scar tissue in the manner that this suggests then it would be quite a miracle drug for burn victims don't you think? How about in plastic surgery in general? Sports medicine?

[trotsky]

12. Yep, that's the worst part.

Convincing someone that they need a product that doesn't actually work, but won't harm either, well, as they say, there's one born every minute and if people aren't capable of critically analyzing these claims for themselves, I guess they deserve to have their money taken away.

But in those instances where said product actually DOES harm, or interfere with other medication, I honestly don't know how these "holistic" health advocates can sleep at night, knowing they may have killed or maimed someone with their advice.

[philb]

30. Its more effective at preventing cataracts or reducing progression

and there are peer-reviewed studies supporting the ingredients in these drops effectiveness.
This manufacturer is not the only one that uses such.
Anyone can find studies on such things from Medline
http://www.nlm.nih.gov

but there are both good and bad studies abstracted there. you need to know enough about what to look for to
determine which ones are credible.

[HysteryDiagnosis]

53. MD, you mean god junior don't you... how many people a year

do MD's put away?? A mechanic fixes his mistakes an MD buries his.

You have not seen a person with MS with brain stem lesions have a clear mri a few months later, give up a wheel chair, regain his life.

You have not seen a blind diabetic woman in her 40's regain her sight and drive once again.

You have not seen back surgeries cancelled with the injection of dextrose into weak or poorly healed ligaments.

You have not seen mitral valve disappear.

You have not seen arterial blockage go from 90% to 40% in a matter of several months.

You have not seen PSA counts slashed to nothing without drugs. Remember the male mammaries Proscar was famous for.

You have not seen a 74 year old male diabetic injecting insulin get off of it in 30 days, drop 40 pounds and go back to jogging.

You have not seen childhood hemangiomas "disappeared" by a plant extract.

You have not seen pancreatic cancers reversed.

You have not seen Lou Gherig's disease turned around.

You have not seen things you should have seen by now, when you do you will understand what you have been missing.

[MrMonk]

63. and you haven't seen such things, either.

[philb]

64. I've seen a lot of those without glyconutrients, but am aware that

glyconutrients appear to have worked "miricles" for a lot of different conditions including cancer and conditions like you list.

Detox & dental revision have cleared up some of those, along with treating mycoplasma in the pancreas.
I'm aware of recovery from thousands of cases of over 40 chronic conditions through dental revision & detox
http://www.home.earthlink.net/~berniew1/hgremove.html
http://www.home.earthlink.net/~berniew1/damspr11.html
but agree that glyconutrients also seem to work, and have lots of clinical test support.
www.glycoscience.org

And I'm also aware that Pharmaceuticals/Doctor Errors are of a similar magnitude as cancer or cardiovascular disease with regards to
hospitalizations and deaths.
http://www.flcv.com/iatrogen.html

[WoodrowFan]

10. but they have a web site!

I mean, that's gotta count for something!

[DoYouEverWonder]

2. Now can they make some magic drops

to reverse the effects of aging on the rest of my body?

[HysteryDiagnosis]

4. For that you would use mexican wild yam... beta-sitosterol...

and glyconutrients. I'm not kidding.

[xchrom]

5. not yet -- but a yooooouuuung lover can help.

:evilgrin:

[Angry Girl]

19. Exercise.... Use it or lose it.

'Tis the harsh reality. Stupid system too: The older you get, the harder you have to work at exercising. Go figure.

[HysteryDiagnosis]

26. Haven't the rupubs figured out a way to get someone else to

excersize for them?? That would be kewl. I mean, they figured out a way to get poor people to fight and die in their unnecessary wars... I'm just sayin'.

[in_cog_ni_to]

3. Cataracts are caused from Scar tissue on the crystalline lens and

it's the scar tissue that causes the cloudiness and inflexibilty of the lens to adjust to light rays. Do these drops remove scar tissue? Hmmmm. Interesting.

[sinkingfeeling]

15. I thought it was moisture/crystals in the lens? My dog is diabetic.

With canines, 90% develop cataracts from the excessive blood sugar, some within weeks of diagnosis. Crissy had the cataracts removed and lens implants in Nov. 2004 to regain her sight.

[Caution]

6. How about information from a reputable source

Using the company which sells this stuff as your source is not generally a good idea.

How about here?
http://www.aao.org/aao/education/cataract.cfm?ss=fic_cataract_anterior_segment
The American Academy of Opthamology's Cataract Resource Center.

Another resource:

http://www.quackwatch.org/01QuackeryRelatedTopics/quacksell.html

read through this and then read through the link posted above and ask yourself how much of a match there is here.

If people wish to discuss this stuff it really belongs in the Astrology, Spirituality & Alternative Healing Group here on DU.

[HysteryDiagnosis]

8. I like quackwatch, he's my favorite misrepresenter of truth... link.

http://www.democraticunderground.com/discuss/duboard.php?az=show_mesg&forum=364&topic_id=57230&mesg_id=57385

[Orrex]

16. Your link, even when duped, doesn't seem to work

Also:

Quackwatch, a debunker of fraudulent and dangerous "traditional medicine" scams, is in your mind a misrepresenter of truth.

But a company that funded a study (remarkably, a very favorable study) of its own "traditional medicine" remedy for a common and well-understood medical condition is a keeper of the sacred flame of knowledge?

That's just plain wacky.

[HysteryDiagnosis]

17. I've debunked quackwatch itself on SEVERAL OCCASIONS. As

far as the link goes.... you can goto PubMed and enter N-acetylcarnosine and cataracts and read to your hearts content. You may want to give Lutein, eyebright, pycnogenol, omega threes, xeanthinin and others a try as well.

[Angry Girl]

18. Don't forget bilberry! And some more anti-aging eye links

Both articles report on the anti-glycating and other effects of particular forms of carnosine.

The Anti-Aging Effects of Carnosine
http://www.lef.org/magazine/mag2003/jan2003_report_carnosine_01.html

THE AGING EYE
...and what can be done to protect it
http://www.lef.org/magazine/mag2002/feb2002_cover_eye_01.html

[HysteryDiagnosis]

20. Thanks angry... it's kinda nice to have support now and again, if

people were educated about ALL of this stuff, our healthcare costs could be cut to shreds.

[Angry Girl]

21. Yup. Exactly why our "health care" system is so screwed up

Our health care "insurance plan" for many years has been Don't Get Sick! As a result we've had to educate ourselves in alternative solutions to the toxic American lifestyle as well as prevention.

Big Pharma has absolutely ZERO interest in your reading anything to do with taking care of your own health. ZERO!

Here's a nice article about how our health care system is held hostage to a bunch of greedy lobbyists who have no intention on curing anybody....

Suddenly Sick: The Big Business behind Your Doctor's Diagnosis
http://seattletimes.nwsource.com/news/health/suddenlysick/

[greyl]

34. Lemme ask you a question or two.

Firstly, we agree that our health care system has major problems.

The question is, do you think that every "alternative" substance works?
I'm guessing you'll answer "probably not" or "definitely not".

If that's the case, what methods should smart consumers use to decide which of the alternatives work and which don't? Should we place default trust onto every alt-health business? Are they all honest? Should we believe "studies" done by those with a financial interest in the outcome of the studies?

[Angry Girl]

35. gawd, no, not all alternative "solutions" are created equal

You shouldn't trust anyone, basically. I spend hours of research before ingesting supplements, using as many sources as possible. (No, I don't have a formal medical education but I know how to read and how to learn) I weigh each source's crediblity, whether a website or book or magazine article. I cross-reference information. I check the library as well as the Internet. I also weigh the risks before trying anything and if the risk/possible benefit ratio is low enough, I'll give it a go -- particularly if the cost is low. For example, traditional chinese medicine is something I'm very into: the costs are low and the diagnostic techniques very well documented. With herbs and their uses, I like to compare Western, TCM, and Ayurvedic sources and see where they coincide or differ.

So it's definitely been an education over the years but it gives me a teensy, weensy piece of mind. :-)

[greyl]

40. That sounded good, but then why

are the two links you posted above leading to 1 website which is selling a product? (at 30 bucks for 10 ml, 50 percent less volume than the typical smallest bottle of eye drops)

[Angry Girl]

42. Not all websites that sell things are bad, with an example

LEF Mag is an excellent magazine. I thought the sources were decent because they summarize what I've read about the carnosine eye drops in other articles.

It is not reasonable to believe that every site that sells something is out to rip you off. And just because a site doesn't sell anything doesn't mean it's more credible.

Scientists have to make money too.

Case in point: The amazing Bruce Ames has a company that sells his famous alpha-lipoic acid + acetyl-L-carnitine combo: http://www.juvenon.com/

Do they make money? Yes, because I can replicate the same combo for less money by ordering the ingredients separately. Is the product an excellent one backed up by tons of credible research? Yes. Is the site credible? Yes. Should they make money? Sure, I have nothing against it.

So this is why I try to take each source on its own merits. Caveat emptor. We're all doomed! :-o

[HysteryDiagnosis]

56. Lots to be said about L-Carnitine and its cousins.... they put it in

my Coenzyme Q10. I'm pretty sure it helps people going through radiation and chemo... I wonder how many actually get it when they are being treated, probably not many... not patentable you know.

[philb]

41. you look for proven experience/ clinical success/ & also

there are lots of peer-reviewed studies and clinical experience available on some of the treatment modalities
such as glyconutrients(www.glycoscience.com)
and VRP journals at www.vrp.com and other such and N.L.M. Medline www.nlm.nih.gov and other such
and medical lab research summaries such as www.gsdl.com and www.melisa.org
and amalgam replacement/detox such as www.home.earthlink.net/~berniew1/hgremove.html

and organizations like DAMS with coordinators interacting with patients and clinics and familar with the reseach(800-311-6265)
and specialty organizations like Autism Research Institute(ARI)interacting with patients and clinics
and condition support forums at yahoogroups or St Johns Univ. where relatives or patients interact with researchers, doctors,nurses, etc.

[philb]

60. peer-reviewed studies of effectiveness of N-Acetylcarnosine for cataracts

Babizhayev MA, Deyev AI, Yermakova VN, et al
Efficacy of N-acetylcarnosine in the treatment of cataracts.
Drugs RD, 2002, 3(2):87-103

Babizhaye MA, Deyev AI, Yermakova VN, et al
N-Acetylcarnosine, a natural histidine-containing dipeptide, as a potent ophtalmic drug in treatment of human cataracts.
Peptides 2001, Jun 22(6):979-94

Analysis of lipid peroxidation and electron microscopic survey of maturation stages during human cataractogenesis: pharmacokinetic assay of Can-C N-acetylcarnosine prodrug lubricant eye drops for cataract prevention.

Babizhayev MA.

Innovative Vision Products Inc., County of New Castle, Delaware 19810, USA. [email protected]

Morphological and biophysical techniques described in this study have shown that membrane derangement occurs in human cataractous lenses. The data suggest that these disruptions were globules, vacuoles, multilamellar membranes and clusters of highly undulating membranes. Deleterious structural damage of the lens fibre cell plasma membranes serve as the primary light-scattering centres that cause the observed lens opacity. Nuclear cataract, a major cause of loss of lens transparency in the aging human, has been thought to be associated with oxidative damage, particularly at the site of the nuclear plasma membrane. Phospholipid molecules modified by oxygen accumulate in the lipid bilayer, change its geometry and impair lipid-lipid and protein-lipid interactions in lenticular fibre membranes. Lipid peroxidation (LPO) is a causative and pathogenic factor in cataract. Increased concentrations of primary molecular LPO products (diene conjugates, lipid hydroperoxides, oxy-derivatives of phospholipid fatty acids) and end-fluorescent LPO products have been detected in the lipid moieties of aqueous humour samples and human lenses obtained from patients with senile and complicated cataracts as compared with normal donors. In the present study, a rapid and simple high-performance liquid chromatographic (HPLC) assay for determination of imidazole-containing dipeptides in the aqueous humour of the eye was developed. The method was applied to determine the pharmacokinetic parameters and the time-course of N-acetylcarnosine and L-carnosine-related product in the eye, following a single dosage of topical ocular administration of peptide. Utilising data from pharmacokinetic studies and the specific purity of the N-acetylcarnosine (NAC) ingredient as a source of the pharmacological principle L-carnosine, we have created an ophthalmic time-release prodrug form including the US FDA-approved carboxymethylcellulose lubricant and other essential ingredients (Can-C, private label Nu-Eyes). This formulation increases the intraocular absorption of L-carnosine in the aqueous humour and optimises its specific antioxidant activity in vivo while reducing the toxic effects of lipid peroxides on the crystalline lens. L-carnosine that enters the aqueous humour can accumulate in the lens tissue for a reasonable period of time. The presence of L-carnosine in transparent crystalline lenses during normal aging was detected and its concentration in this case was about 25 microM. At different stages of cataract development, the level of L-carnosine drastically decreased, reaching about 5 microM in ripe human cataracts. However, administration of pure L-carnosine (1% solution) to the rabbit eye (instillation or subconjunctival injection) does not lead to accumulation of this natural compound in the aqueous humour at the time level over 30 minutes at a concentration exceeding that in placebo-treated matched eyes, and its effective concentration is exhausted more rapidly. Use of NAC prodrug eye drops optimises the clinical effects of L-carnosine in the treatment of ophthalmic disorders (such as prevention and reversal of cataracts in human and animal eyes). The data provided predict a clinical effect with NAC ophthalmic prodrug, and show that the magnitude and duration of this effect are directly related to the bioavailability of L-carnosine released from NAC in the aqueous humour of the anterior eye segment. The ophthalmic NAC drug shows promise in the treatment of a range of ophthalmic disorders that have a component of oxidative stress in their pathogenesis (including cataract, glaucoma, dry eye, vitreous floaters, inflammatory disorders, and corneal, retinal and systemic diseases ). There is a need for further and better collaboration between Innovative Vision Products' cataract control and ophthalmic services, improved education of people affected by cataract, a commitment that N-acetylcarnosine eye drops will be the preferred treatment before orthodox cataract surgery is attempted, and consideration of outcomes and a possible role of the NAC drug cataract treatment as source of referral for orthodox surgical, ophthalmic and optometric services.

[Desertrose]

22. So true....and really....

...there is more support out here than you think 4MoronicYears.

Its just the usual naysayers around here that like to post on everything they deem "un-acceptable".I agree...healthcare is such a racket. Like big pharma WANTS us to be healthy. Follow the $$ to find the truth.


DR

[HysteryDiagnosis]

23. What taught me the most.... was the research on glyconutritionals,

phytochemicals and phytogenins.... there is absolutely no denying that these things CURE DISEASE, however I cannot say that in an open forum.

[Desertrose]

24. I know, I have been looking into them recently too

and I agree that we do have within our environment, the things we need to heal our bodies and remain healthy....and not manufactured pharmaceuticals.

So isn't it a shame we can't say these things?

You should share in the astro/health forum. we used to have soem good discussions there....

[HysteryDiagnosis]

25. I have the cancer video by Dr. ******** on the use of glyconutrients

with traditional therapies.... and then there are the examples of those who either chose not to have their jaw, bilateral neck etc removed... who simply went the supplement route.... pancreatic cancers taken down.... truly amaaaaaaaaaaazing. It blew a close relative completely away.. and he is nobody's fool.

[greyl]

27. "So isn't it a shame we can't say these things?" !

Correct me if I'm wrong, but it looks like you are saying "these things". Was your post deleted? Are you banned?
No. Are you fond of using misleading language?

Fact is, some people find it hard to handle hard facts that are in disagreement with their soft beliefs.

The topic of this thread (Can-C®) is a brand of eye drops marketed all but outright fraudulently (sneaky language) by profit driven web site operators. The evidence offered in this thread for its ineffectiveness has not been countered by you. Instead, it appears you've chosen to poison the well against those that don't enjoy seeing dishonest business flourish. I guess that was your only choice considering the side you've chosen in this debate about "Can-C® (1% solution NAC* eye-drops), patented by Innovative Vision Products (IVP) and sold strictly as an “eye lubricant”"

I love clubnatural's use of Yahoo!'s logo to give an air of authenticity.

You'll never see the following on a reputable health professional's web site:

"Disclaimer: Statements made, or products sold through this web site, have not been evaluated by the Food and Drug Administration. They are not intended to diagnose, treat, cure, or prevent any disease."

Kinda reminds one of Psychic Hotline's disclaimer, doesn't it?

[philb]

31. I've also posted statements by Univ. scientists debunking Quackwatch

disinformation; the Quackwatch people fare poorly in hearings and court since they have no credible credentials
and depend on disinformation that is easily debunked by people with credible science background.

[greyl]

32. Your post adds zero info about the subject at hand.

The subject is Can-C® (1% solution NAC* eye-drops), patented by Innovative Vision Products (IVP) and sold strictly as an “eye lubricant”.
I didn't refer to Quackwatch to acquire my opinion. I didn't mention them in my thread.

[philb]

44. I discussed that topic but other things were broughtup including quackpots

I wasn't responding to your post there. I had a more direct response to your post.
You raised a valid question.

[Desertrose]

36. too late to post...n/t

[greyl]

28. I'd love to peruse the text of those occasions. Furthermore,

PubMed only has one small clinical trial that was done by the makers of the subject of the trial.

Pretend GWBush was telling you to buy this product based on his own intelligence.
I'm guessing your reaction would be skeptical, eh?

[HysteryDiagnosis]

37. You do understand that oxidative stress is a prime player in

probably 59 of the top 60 illnesses/degenerative conditions we humans live with, or at least I hope you do... take it from there.

Prevent Cataract Surgery
www.ushc.net CataVita™ - Specially formulated to reverse cataract formation.
Cataracts Dissolved
www.cataract-clear.ch No need for invasive surgery, suitable for both people and pets
Can-C N-acetylcarnosine eye-drops
How does N-acetylcarnosine work in the eye: Cataracts are caused by the hardening
... Other than senile cataract, N-acetylcarnosine may have other benefits. ...
www.antiaging-systems.com/a2z/can-c.htm - 23k - Cached - Similar pages

IAS Bulletin Article: NAC - Is It The Cure For Cataract?
Babizhayev MA et al "N-Acetylcarnosine, a natural histidine-containing di-peptide,
as a potent ophthalmic drug in treatment of human cataracts. ...
www.antiaging-systems.com/extract/nac.htm - 35k - Cached - Similar pages
< More results from www.antiaging-systems.com >

Efficacy of N-acetylcarnosine in the treatment of cataracts.
PURPOSE: To evaluate the effects of 1% N-acetylcarnosine (NAC) solution on lens
clarity over 6 and 2...
www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve& db=PubMed&list_uids=12001824&dopt=Abstract - Similar pages

Lipid peroxidation and cataracts: N-acetylcarnosine as a ...
Lipid peroxidation and cataracts: N-acetylcarnosine as a therapeutic tool to
manage age-related cataracts in human and in canine eyes. ...
www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve& db=PubMed&list_uids=15139774&dopt=Citation - Similar pages
< More results from www.ncbi.nlm.nih.gov >

Carnosine and N-Acetylcarnosine Eye Drops New Hope for Cataracts ...
Carnosine and N-Acetylcarnosine Eye Drops New Hope for Cataracts. ... Block, W.
N-Acetylcarnosine May Help with Cataracts. NAC eye drops show benefits in ...
www.vrp.com/art/1099.asp - 21k - Cached - Similar pages

Life Enhancement:: N-Acetylcarnosine May Help with Cataracts - Aug ...
... N-Acetylcarnosine Reduces Cataracts. ... N-Acetylcarnosine, a natural histidine-containing
dipeptide, as a potent ophthalmic drug in treatment of human cataracts. ...
www.life-enhancement.com/article_template.asp?ID=855 - 30k - Supplemental Result - Cached - Similar pages

CAN-C Cataract Eye Drops - What the experts say about N-Acetyl ...
Efficacy of N-acetylcarnosine in the treatment of cataracts. Drugs R&D, 2002:
3(2): 87-103. Lipid peroxidation as a possible cause of human cataracts. ...
www.can-c.net/expert.htm - 15k - Cached - Similar pages

Bionational Pharmaceuticals
... is the principal Russian researcher behind the development and use of
N-Acetylcarnosine (NAC) eye-drops, Nu-Eyes™ for the treatment of cataracts. ...
www.bionational.com/xcart/catalog/ - 24k - Cached - Similar pages

Non-Surgical Cataract Cure: N-Acetyl Carnosine Dissolves Cataracts
N-Acetyl Carnosine is an enzyme that dissolves cataracts -- without surgery. ...
Lipid peroxidation and cataracts: N-acetylcarnosine as a therapeutic tool ...
www.weeklyuniverse.com/2004/cataract.htm - 24k - Cached - Similar pages

Senile Cataract & N-acetylcarnosine Eye-Drops, The World Health ...
WorldHealth.net is dedicated to providing latest anti-aging, health, biotechnology,
and longevity information and products to the general public and health ...
www.worldhealth.net/p/1007,2037.html - 49k - Cached - Similar pages

[greyl]

39. All of your links are to ads and "add to your shopping cart" pages

The two links to ncbi.nlm are to the study done by the guy (Babizhayev) in charge of developing and marketing his brand of the product.

[HysteryDiagnosis]

46. This is war.... sort of.

1: Altern Med Rev. 2001 Apr;6(2):141-66. Related Articles, Links


Natural therapies for ocular disorders, part two: cataracts and glaucoma.

Head KA.

Thorne Research, Inc., P.O. Box 25, Dover, ID 83825,USA. [email protected]

Pathophysiological mechanisms of cataract formation include deficient glutathione levels contributing to a faulty antioxidant defense system within the lens of the eye. Nutrients to increase glutathione levels and activity include lipoic acid, vitamins E and C, and selenium. Cataract patients also tend to be deficient in vitamin A and the carotenes, lutein and zeaxanthin. The B vitamin riboflavin appears to play an essential role as a precursor to flavin adenine dinucleotide (FAD), a co-factor for glutathione reductase activity. Other nutrients and botanicals, which may benefit cataract patients or help prevent cataracts, include pantethine, folic acid, melatonin, and bilberry. Diabetic cataracts are caused by an elevation of polyols within the lens of the eye catalyzed by the enzyme aldose reductase. Flavonoids, particularly quercetin and its derivatives, are potent inhibitors of aldose reductase. Glaucoma is characterized by increased intraocular pressure (IOP) in some but not all cases. Some patients with glaucoma have normal IOP but poor circulation, resulting in damage to the optic nerve. Faulty glycosaminoglycan (GAG) synthesis or breakdown in the trabecular meshwork associated with aqueous outflow has also been implicated. Similar to patients with cataracts, those with glaucoma typically have compromised antioxidant defense systems as well. Nutrients that can impact GAGs such as vitamin C and glucosamine sulfate may hold promise for glaucoma treatment. Vitamin C in high doses has been found to lower IOP via its osmotic effect. Other nutrients holding some potential benefit for glaucoma include lipoic acid, vitamin B12, magnesium, and melatonin. Botanicals may offer some therapeutic potential. Ginkgo biloba increases circulation to the optic nerve; forskolin (an extract from Coleus forskohlii) has been used successfully as a topical agent to lower IOP; and intramuscular injections of Salvia miltiorrhiza have shown benefit in improving visual acuity and peripheral vision in people with glaucoma.

Publication Types:
Review

PMID: 11302779

1: Nutrition. 2001 Oct;17(10):888-95. Related Articles, Links


Molecular aspects of lipoic acid in the prevention of diabetes complications.

Packer L, Kraemer K, Rimbach G.

Department of Molecular Pharmacology and Toxicology, School of Pharmacy, University of Southern California, 1985 Zonal Avenue, Los Angeles, CA 90098-9121, USA. [email protected]

Alpha-lipoic acid (LA) and its reduced form, dihydrolipoic acid, are powerful antioxidants. LA scavenges hydroxyl radicals, hypochlorous acid, peroxynitrite, and singlet oxygen. Dihydrolipoic acid also scavenges superoxide and peroxyl radicals and can regenerate thioredoxin, vitamin C, and glutathione, which in turn can recycle vitamin E. There are several possible sources of oxidative stress in diabetes including glycation reactions, decompartmentalization of transition metals, and a shift in the reduced-oxygen status of the diabetic cells. Diabetics have increased levels of lipid hydroperoxides, DNA adducts, and protein carbonyls. Available data strongly suggest that LA, because of its antioxidant properties, is particularly suited to the prevention and/or treatment of diabetic complications that arise from an overproduction of reactive oxygen and nitrogen species. In addition to its antioxidant properties, LA increases glucose uptake through recruitment of the glucose transporter-4 to plasma membranes, a mechanism that is shared with insulin-stimulated glucose uptake. Further, recent trials have demonstrated that LA improves glucose disposal in patients with type II diabetes. In experimental and clinical studies, LA markedly reduced the symptoms of diabetic pathologies, including cataract formation, vascular damage, and polyneuropathy. To develop a better understanding of the preventative and therapeutic potentials of LA, much of the current interest is focused on elucidating its molecular mechanisms in redox dependent gene expression.

Publication Types:
Review

PMID: 11684397

[HysteryDiagnosis]

47. New Delhi

1: J Ethnopharmacol. 2003 May;86(1):109-12. Related Articles, Links


Anticataract activity of Kohl-Chikni Dawa--a compound ophthalmic formulation of Unani medicine in alloxan-diabetic rats.

Siddiqui TA, Shadab Z, Nishat I, Ayasha N, Zehra Z, Alavi SH.

Department of Surgery, Faculty of Medicine (Unani), Hamdard University, Hamdard Nagar, New Delhi-110062, India. [email protected]

Kohl-Chikni Dawa (KCD), a compound ophthalmic formulation of Unani medicine was studied for anticataract activity in alloxan-diabetic rats. When one drop of 3% KCD solution was applied (once and twice daily) in both eyes for 90 days in alloxan-diabetic rats, a significant reduction of lens opacification was noticed. On the other hand, local application of 3% KCD solution (once and twice daily) did not reduce the blood sugar concentration in normal and alloxan-diabetic rats. Blood sugar in all the rats was estimated by glucometer and the morphological changes of the lenses were examined by slit-lamp biomicroscope before and after therapy at various time intervals for 90 days. These results suggest that the local application of 3% KCD solution possesses anticataract effect in alloxan-induced hyperglycaemic rats.

PMID: 12686448

[HysteryDiagnosis]

48. Dover USA

1: Altern Med Rev. 2001 Apr;6(2):141-66. Related Articles, Links


Natural therapies for ocular disorders, part two: cataracts and glaucoma.

Head KA.

Thorne Research, Inc., P.O. Box 25, Dover, ID 83825,USA. [email protected]

Pathophysiological mechanisms of cataract formation include deficient glutathione levels contributing to a faulty antioxidant defense system within the lens of the eye. Nutrients to increase glutathione levels and activity include lipoic acid, vitamins E and C, and selenium. Cataract patients also tend to be deficient in vitamin A and the carotenes, lutein and zeaxanthin. The B vitamin riboflavin appears to play an essential role as a precursor to flavin adenine dinucleotide (FAD), a co-factor for glutathione reductase activity. Other nutrients and botanicals, which may benefit cataract patients or help prevent cataracts, include pantethine, folic acid, melatonin, and bilberry. Diabetic cataracts are caused by an elevation of polyols within the lens of the eye catalyzed by the enzyme aldose reductase. Flavonoids, particularly quercetin and its derivatives, are potent inhibitors of aldose reductase. Glaucoma is characterized by increased intraocular pressure (IOP) in some but not all cases. Some patients with glaucoma have normal IOP but poor circulation, resulting in damage to the optic nerve. Faulty glycosaminoglycan (GAG) synthesis or breakdown in the trabecular meshwork associated with aqueous outflow has also been implicated. Similar to patients with cataracts, those with glaucoma typically have compromised antioxidant defense systems as well. Nutrients that can impact GAGs such as vitamin C and glucosamine sulfate may hold promise for glaucoma treatment. Vitamin C in high doses has been found to lower IOP via its osmotic effect. Other nutrients holding some potential benefit for glaucoma include lipoic acid, vitamin B12, magnesium, and melatonin. Botanicals may offer some therapeutic potential. Ginkgo biloba increases circulation to the optic nerve; forskolin (an extract from Coleus forskohlii) has been used successfully as a topical agent to lower IOP; and intramuscular injections of Salvia miltiorrhiza have shown benefit in improving visual acuity and peripheral vision in people with glaucoma.

Publication Types:
Review

PMID: 11302779

[HysteryDiagnosis]

49. This board

http://www.democraticunderground.com/discuss/duboard.php?az=show_mesg&forum=222&topic_id=3384&mesg_id=3463

[HysteryDiagnosis]

50. University of SC.

http://www.sc.edu/usctimes/articles/2004-01/profeta_sal.html

Profeta’s first industry experience was at Allergan Pharmaceuticals in Irvine, Calif., where he used molecular modeling to help develop antiglaucoma drugs, cataract reversal drugs, and anti-inflammatory drugs for eye and skin care. “It was an excellent first experience in industry,” he said. “There are anti-psoriasis and anti-acne medicines on the market now that were part of my work at Allergan.”

[HysteryDiagnosis]

52. The smart people at LEF

http://www.lef.org/protocols/prtcl-030c.shtml

Carnosine
Carnosine inhibits formation of advanced glycation end products (AGEs) and protects normal proteins from the toxic effects of existing AGEs.90,91 Eye drops containing N-acetyl-L-carnosine can delay vision senescence in humans: effective in 100% of primary senile cataract cases and 80% of mature senile cataract cases. N-acetyl-L-carnosine enter the aqueous and lipid parts of the eye and prevent and repair light-induced breaks to DNA strands.92 N-acetyl-L-carnosine eye drops are approved for human use in Russia for the treatment of many eye diseases. Brite Eyes II is an advanced eye formula that contains 1% N-acetyl-L-carnosine in a soothing eye drop. A suggested oral dose of carnosine is 500-1000 mg daily.

[HysteryDiagnosis]

9. Dupe

http://www.democraticunderground.com/discuss/duboard.php?az=show_mesg&forum=364&topic_id=57230&mesg_id=57385

[HysteryDiagnosis]

55. I prefer quackpotwatch.... you should see what your buddy at

quackwatch is really all about.


http://www.quackpotwatch.org/opinionpieces/Met%20Stephen%20Barrett.htm

http://www.quackpotwatch.org/opinionpieces/quackpot_barrett_crushed_in_fede.htm

http://www.quackpotwatch.org/
"THE LAST DAYS OF THE QUACKBUSTERS"...
"Thus began my education. Now I'm going to educate YOU...

It is a propaganda enterprise, one part crackpot, two parts evil. It's sole purpose is to discredit, and suppress, in an "anything goes" attack mode, what is wrongfully named "Alternative Medicine." It has declared war on reality. The conspirators are acting in the interests of, and are being paid, directly and indirectly, by the "conventional" medical-industrial complex."
--

ALTERNATIVE MEDICINE?
"Alternative Medicine" is defined as any protocol, action, or therapy that isn't "drugs, radiation, or surgery oriented."

Wrongfully named? Yes. So-called "alternative medicine" is actually the health choice of planet earth. It is a combination of every good health idea invented by mankind, in every country and culture on this planet. There is nothing "alternative" about it. Labeling planet earth's health choice as "alternative" is, and was, a propaganda device.
--

WHY THE FEAR IN THEIR EYES?
Three Reasons: Exposure, ridicule, and public rage.

(1). EXPOSURE - Health Freedom Fighters, tired of the persecutions, and outnumbering the "Quackbusters" 100,000 to 1, are now watching Barrett and his soldiers carefully. They've decided to put a stop to Barrett and company. Lists are being made of who the "Quackbuster Conspirators" are, what their function is, where they fit into the conspiracy, who they work for, who their associates are, where they live, and what their probable motives are. Their daily activities, as "Quackbusters," are being monitored, and documented. Health leaders consider Barrett, and company, to be running a subversive organization working against the interests of America.

(2). RIDICULE - Examination of Barrett's operation proves that the "Quackbusters" are a paper tiger. They are a construction with a 25 year old modus operandi. Their membership is small, they have an even smaller core group, the industry is turning its back on their extremism, and their leadership "public presence" is laughable.

The American public, in a consumer-driven movement, is rejecting, with laughter and ridicule, Barrett and company's ludicrous assertions - hence the term "Quackpot" is now used, commonly, to describe the self-named "Quackbusters."

(3). PUBLIC RAGE - The American public is just now realizing two things (a) that a good many of those "alternative" things being blocked, and suppressed, have been around for a long while - but not available to them because of the conspiracy, and (b) that the system to find and put new things in place is corrupt - and works against Americans. Every "cure" since polio has been suppressed, and the proponents of those cures, reviled by the "Quackbuster Conspirators."
---

Healthfraud Newsletter

We're going to make you angry with this information. Because HEALTH FRAUD is the BIGGEST problem facing North Americans. Our medical system is broken. More Americans unnecessarily die each year from our conventional medical system (783,936) than from ANY other cause - and, it costs us $282 billion per year, for that. Nothing is being done about it.

[Rhiannon12866]

13. My vet recently prescribed eye drops for my little dog who really can't

see well, has entirely lost his peripheral vision, and this causes him a lot of problems. I had considered cataract surgery, so considered this to be a kind of miracle, non invasive and easy to administer. And, yes, this is the dog in my sig, my eight-pound Brussels Griffon. I was skeptical, but talked to my other vet about this, who said that he thought it was better for dogs who were just starting to have problems, and to my vet who recommended it. He told me that his partner tried it, and had good results, so he ordered some for his patients. His assistant told me that she's seen results, even for dogs with established cataracts, and she's become a friend of mine, so I can ask her pretty much anything. It's still early days, but I'm hopeful.:shrug:

[julianer]

14. That is the capitalist way

a dressed up con game.

Here's an alternative approach:

Meeting in Sandino, Cuba, last month, Chavez and Castro announced that Operation Miracle will cover all Latin Americans, offering to treat 600,000 people a year over the next 10 years for eye operations funded by Venezuela.

"Everything is paid for," said Faride, from Guyana, who brought her 83-year-old mother for a cataract operation. "We are thankful." She also declined to give her last name.

Cuba has one doctor for every 170 people, compared to 188 in the United States and 542 in Venezuela, World Health Organization figures show. It boasts universal health care and an infant mortality rate below that of the United States.

Cuba has 25,000 doctors serving in 66 developing countries. Castro recently offered to send 1,500 doctors to aid Hurricane Katrina victims, an offer that was not taken up by the U.S. government

http://www.canf.org/2005/1in/noticias-de-Cuba/2005-sep-16-cuban-eye-operations.htm

Edit: added link

[philb]

29. cataracts are primarily caused by free radicals- often from toxic exposure

such as mercury; there are lots of medical studies in Medline documenting this
some info at http://www.home.earthlink.net/~berniew1/eyeshg.html I have another page but can't remember url

I recovered from Fuch's Disease which is a more extreme degenerative form after having my amalgam fillings replaced.
Two Opthamologist's had told me I was going blind due to Fuch's, but instead after amalgam replacement,etc.
my eyes have improved so much that I no longer wear glasses(which I've had to wear since a teenager) except for night
driving.

many have improved from eye conditions after amalgam replacement
likely some at http://www.home.earthlink.net/~berniew1/recover.html


I've started using the eye drops that the original post suggests. there are peer-reviewed studies supporting their effectiveness.

[greyl]

33. "there are peer-reviewed studies supporting their effectiveness"

Where?

[philb]

43. many thousands such readily available

National Library of Medicine Medline http://www.nlm.nih.gov/
free journal published by Vitamin Research Products http://www.vrp.com and lots of similar such
huge numbers of peer-reviewed journals on nutrition, health, medical conditions, etc. available on web, in Univ. libraries,
etc.
research at medical lab web sites such as www.gsdl.com and other such

an example referencing many hundreds such incidentally are the DAMS research summaries of articles documenting the mechanisms by
which mercury and other toxic exposures cause over 40 chronic or degenerative conditions, with supplements that improve those conditions noted and peer-reviewed journal references cited.
http://www.home.earthlink.net/~berniew1/indexa.html

and sites such as www.glycoscience.com
and many more such

there are also lots of good medical newsletters with lots of documentation on causes of conditions and documentation on
treatments and supplements that improve the conditions. I read many such regularly, tabluate them, and can refer people to
peer-reviewed studies supporting treatments/supplements that are documented to improve most chronic conditions.

its well documented that most chronic conditions involve metabolic blockages, enzymatic blockages, immune reactivities,etc.
that can be tested for and improved by reducing toxic exposures or by detox to reduce metabolic blockages and enzyamatic blockages or by supplements documented to improve such. There are lots of good tests available these days and huge amounts of medical and clinical studies available on conditions and products that improve conditions.
The main problem is knowing which tests to do and how to interpret test results and how to access the huge amount of information/research/clincial experience available that is related to specific circumstances. Unfortunately not many doctors are very well trained or equipped for such, and in my opinion there aren't enough researchers, compilers(like me) and proper channels for getting the relevant information into the hands of those who need it. Though there are some good and dedicated doctors, there are also many who don't have adequate training and knowledge in dealing with chronic conditions, and I think the U.S. system has been lead far astray by the domination of Pharmaceuticals more interested in making money and pushing meds to relieve symptoms rather than preventing chronic conditions or curing them when they occur. These days there is a huge amount of documentation of
how the bodies systems work, how the metabolism works, how to prevent chronic conditions, how to cure or improve chronic conditions. The problem is getting the knowledge to those who need it.

[HysteryDiagnosis]

51. A quote from you Philb

>>its well documented that most chronic conditions involve metabolic blockages, enzymatic blockages, immune reactivities,etc.
that can be tested for and improved by reducing toxic exposures or by detox to reduce metabolic blockages and enzyamatic blockages or by supplements documented to improve such. There are lots of good tests available these days and huge amounts of medical and clinical studies available on conditions and products that improve conditions.<<

And yes, you are correct, you get the prize, the prize is KNOWING THAT there is a way to address things that modern medicine often labels unaddressable.... and this is usually because they aren't allowed to use "power tools" things that affect genetic expression, immune reactivity, enzyme insufficiencies, toxic burden etc etc, they are only allowed to use "hand tools", drugs with limited targeted activities in the body.

[greyl]

58. the prize.

"the prize is KNOWING THAT there is a way to address things that modern medicine often labels unaddressable...."

The guy who is in business selling this product is a medical doctor, and makes a point of saying so to transfer credibility from the "scientific degree" to the "I'm rolling in cash now" "product".

He is pretending to be "modern medicine" while existing as a niche targeted amoral business.

How do you tell the difference between a competent doctor and an incompetent doctor?
How do you tell the difference between honest information about breakthroughs in health care and a dishonest ad?

[HysteryDiagnosis]

59. Honest doctors in most peoples' opinion are persons who spent

less than one hour studying the role of specific antioxidants, bioflavonoids, enzymes, herbs, vitamins, minerals, amino acids, essential fatty acids, and others in med school. They simply cannot have a realistic view of the role that nutrional supplements have had and continue to have in health and disease.

[greyl]

57. Then why can't you post one?

Are you trying to be funny?

Again, you've provided links which lend absolutely no support for the claims made by the merchants of these eye drops. You say there are thousands of studies, yet can only provide the following "evidence":

http://www.nlm.nih.gov/
http://www.vrp.com/
http://www.gsdl.com/
http://www.glycoscience.com/
http://www.home.earthlink.net/~berniew1/indexa.html - which isn't "evidence" at all.

I just don't understand where you get the confidence to make the statements you've made here about this product.
You've said there is more than enough scientific basis for believing this product works, but haven't produced evidence of it. You've copied their advertising. In a dimension, you are working for "them" at no charge, with no benefits, as a marketing agent.

Why do you believe this product works?

[HysteryDiagnosis]

61. With the glycoscience or the field of glycobiology.... it's all about

enhancing immune system competence, reversing autoimmune conditions, increasing reduced glutathione in the liver, and perhaps most importantly.... ramping up the production of adult stem cells in the bone marrow.

If you don't believe the production of stem cells can be enhanced in the human frame, or if you doubt that something other than a drug can accomplish this feat.... read here.


http://www.doctorshealthcall.com/

[Angry Girl]

62. Here's a few

Is this what you were seeking? Not tons of studies but there are a few more out there. Granted, NAC is not like aspirin, with tons of research data out there.

Interestingly, this blog entry says that at least 2 versions of the drops are no longer being imported to the States because the FDA wants the drops to be Prescription only.... I wonder why.
http://relentlessimprovement.blogspot.com/2005/10/carnosine-eye-drops-for-cataracts.html
--------
Miscellaneous NAC info follows....

An interview with Mark Babizhayev Ph.D. about the development of NAC eye-drops
http://www.antiaging-systems.com/extract/babizhayev.htm

NAC - Is It The Cure For Cataract?
http://www.antiaging-systems.com/extract/nac.htm

Lipid peroxidation and cataracts: N-acetylcarnosine as a therapeutic tool to manage age-related cataracts in human and in canine eyes.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15139774&dopt=Citation

Analysis of Lipid Peroxidation and Electron Microscopic Survey of Maturation Stages during Human Cataractogenesis: Pharmacokinetic Assay of Can-C N-Acetylcarnosine Prodrug Lubricant Eye Drops for Cataract Prevention.
http://pt.wkhealth.com/pt/re/rdd/abstract.00126839-200506060-00004.htm;jsessionid=DBpTA2VRKFK5FeElB3gxTVcsx2h1j3liHQY8Qo49LoOJfEia8Q23!-943888906!-949856145!9001!-1

N-ACETYL-L-CARNOSINE EYEDROPS
A Revolution in Orthomolecular Eye Health!
http://www.aor.ca/related_research/carno_see.php

Efficacy of N-acetylcarnosine in the treatment of cataracts.
http://www.edinburgh-eyetests.co.uk/more-research.htm

Some testimonials
http://www.can-c.net/success.htm

Cataracts
http://www.lef.org/protocols/prtcls-txt/t-prtcl-030.html

About NAC
http://www.eyesight.nu/nacetylcarnosine__can-c.htm

[philb]

65. I posted specific peer-reviewed studies from Medline and these

sites are Medline where anyone could find them
and VRP has a free journal that has peer-reviewed references- some related to NAC, plus has search with references on its site

and GSDL is a medical lab site that has research documentation with peer-reviewed references
and Glycoscience has lots of peer-reviewed studies and clinical studies

and the DAMS website cites over 4000 peer-reviewed medical and Gov't studies

I don't understand what your problem is

The big sites are sites with peer-reviewed studies showing many types of nutritional supplements are documented to be
effective for improving many chronic conditons- which is what I was posting them for;
but I also posted a few specific studies for the drops(from Medline) and noted you could find them at the Medline site.

But the other sites also all have references showing that cataract damage is caused by free radicals,
and the NAC drops were developed to deal with the free radicals caused by toxic accumulations in the cornea endothelial cells.

[purr]

38. What about congenital cataracts?

I had 2 of them, got my left one removed and my vision is worse in that eye than before.

[philb]

45. someone in our family has congenital cataracts due to toxic exposure

trichroloethylene in our well- fetal exposure. She has used such drops. The main thing they likely do
is prevent worsening, not reverse much of the current damage.

But I had the start of cataracts and Fuch's Disease to the extent that 2 opthamologists advised me I would likely go blind in a
fairly short time, progressing fairly rapidly. After research I determined that free radicals were a major factor and in my case mercury from amalgam fillings. Amalgam replacement and detox(and I've used the drops also later) not only prevented my eye conditions from getting worse but my condition has improved significantly. To the extent I no longer wear glasses (except for night driving)

[HysteryDiagnosis]

54. Evidence that you are not "seeing things" you shouldn't. nt.

1: Toxicology. 2002 Oct 30;180(1):97-105. Related Articles, Links


Naphthalene toxicity and antioxidant nutrients.

Stohs SJ, Ohia S, Bagchi D.

School of Pharmacy and Health Professions, Creighton University Medical Center, 2500 California Plaza, Omaha, NE 68178, USA. [email protected]

Naphthalene is a bicyclic aromatic compound that has wide industrial and commercial applications. It is used as the starting material for the synthesis of other compounds, as a moth repellent, soil fumigant and lavatory deodorant. Most exposure occurs through low dose chronic inhalation, dermal contact or ingestion through the food chain. The lungs and eyes appear to be most susceptible to toxicity, although biochemical markers of toxicity can be demonstrated in other tissues, such as the kidney, brain and liver. In addition to lens opacification (cataracts) and histological changes associated with pneumotoxicity, other biomarkers of toxic effects include glutathione depletion, lipid peroxidation, DNA fragmentation and the production of the active oxygen species as superoxide anion and hydroxyl radical. In addition, the urinary excretion of lipid metabolites occurs. A role for the tumor suppressor gene p53 has been demonstrated. Toxic manifestations of naphthalene are associated with its oxidative metabolism to various products including quinones. The ability to protect against the toxic effects of naphthalene by using various antioxidants and free radical scavengers has been demonstrated. Studies have been conducted with vitamin E, vitamin E succinate, melatonin, curcumin, various L-cysteine prodrugs, several aldose reductase inhibitors and spin-trapping agents. The ability to prevent the toxic manifestations of naphthalene is dependent on the pharmacokinetic properties of the agents, which have been studied. The appropriate selection of chemoprotectants can be useful in preventing naphthalene toxicity.

Publication Types:
Review

PMID: 12324202