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Joanne98 Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Sep-17-09 02:47 PM
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Diesel Exhaust Causes Cancer to Grow

For OpEdNews: Posted by Stephen Fox - Writer

Diesel exhaust smells nasty, looks filthy and can make you cough. But there's an even more important reason to avoid the pollutant that's spouted from countless buses and cars: diesel exhaust is linked to the growth of cancerous tumors. Now, researchers at Ohio State University have discovered how diesel fumes can spur on malignancies -- diesel exhaust causes new blood vessels to grow that serve as a food supply for cancerous tumors.

The scientists experimented with mice by creating two conditions that mimic conditions in a human body exposed to diesel fumes. One group of lab rodents was implanted with tiny platforms seeded with normal endothelial cells (the cells that line blood vessels) under their skin. The mice in another group were manipulated so there was ischemia (a loss of blood flow) to their hind limbs and that generated an area of severe hypoxia (lack of oxygen), a condition found in many diseases.

Then, for six hours per day five days a week, both groups of mice were exposed to either diesel exhaust or filtered outdoor air. The rest of the time the animals breathed filtered indoor air. The scientists measured the effects of these these exposures after two weeks, five weeks and eight weeks.

The results of the experiment, which were just published online and are slated to be included in the upcoming print edition of the journal Toxicology Letters, show diesel fumes act like a kind of fuel for blood vessels. Compared to mice breathing filtered air, an eight week exposure to diesel exhaust caused a six-fold increase in new blood vessel formation in the ischemic hind limbs and a four-fold increase in vessel formation in the mice with normal hind legs. The scientists also found more blood vessel growth in the implanted normal cells.

In all, the research team discovered that three types of blood vessel development had taken place areas after exposure to the diesel exhaust: angiogenesis, the development of new capillaries; arteriogenesis, the maturation or re-started growth of existing vessels; and vasculogenesis, the formation of new blood vessels. These findings are significant -- and worrisome -- because all of these processes are associated with the growth of cancerous tumors. And it is runaway angiogenesis that especially wreaks havoc in the human body, helping malignancies spread.

What's more, the exhaust exposure levels in the study were designed to mimic the diesel fume exposure that humans regularly receive if they reside in cities and/or commute in heavy traffic. In a statement to the media, the research team pointed out that the tiny size of inhaled diesel particles (most are less than 0.1 microns in diameter) allow the material to penetrate into the human circulatory system, organs and tissues, potentially causing damage anywhere in the body.

"The message from our study is that exposure to diesel exhaust for just a short time period of two months could give even normal tissue the potential to develop a tumor," Qinghua Sun, senior author of the study and an assistant professor of environmental health sciences at Ohio State University, said in the media release.

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onehandle Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Sep-17-09 03:08 PM
Response to Original message
1. Years ago, I had a girlfriend cuss me out about complaining about her crappy old Mercedes exhaust.
Point: onehandle

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femrap Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Sep-17-09 07:24 PM
Response to Original message
2. I knew there was something wrong with
Edited on Thu Sep-17-09 07:25 PM by femrap
diesel when I was a kid. I got sick when riding the school bus. To this day, I refuse to drive behind one. The diesel is emitted down low where most diesel trucks have the smell,dirt,etc emitted higher up so people in cars don't have to smell as much of it.

Another thing that has to be bad for lungs is Hair Spray....My mother had to go outside to spray her hair because it hurt my lungs. She didn't like to do this, of course.

There's also something in Crystal Light that hurts my lungs when the powder is poured into a glass/pitcher.

And if I see one more Pink Ribbon with 'Find a Cure' on it, I'm going to scream. FIND THE CAUSE, you idiots....which I believe is the estrogens (growth hormones) put into cattle....Don't drink milk!!!!!
I can see little girls who are developing way too soon...they are drinking too much milk!

OK, I'll get off of my soap box now.

edit for typo

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mike_c Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Sep-17-09 07:26 PM
Response to Original message
3. if this is supported by additional research it will be a major environmental...
...toxicology result. This is a potential biggie.
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DCKit Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Sep-18-09 03:31 PM
Response to Original message
4. Can't rec now, so I'll kick. n/t
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