Thursday, June 22, 2006; Posted: 11:55 a.m. EDT (15:55 GMT)
WASHINGTON (CNN) -- Paralyzed rats partially regained the use of a previously immobile hind leg in a study in which scientists injected the rodents with stem cells from mouse embryos, according to researchers at Johns Hopkins University.
The scientists said they combined the transplanted stem cells with a "cocktail" of chemicals to help the paralyzed rats regenerate some of their nerve cells. This allowed a message from the brain to travel to the spinal cord and then to the legs of the paralyzed rats.
Results of the study were published this week in the journal Annals of Neurology.
Before the research began, the rats were given a virus that caused a neurodegenerative disease, paralyzing them.
In the study, 11 of the 15 rats made a partial, but significant, recovery from paralysis, researchers said. The rats recovered enough muscle strength to bear weight and walk on the previously paralyzed hind leg. (Watch as paralyzed rats move -- 1:59)
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http://www.cnn.com/2006/HEALTH/06/22/stem.cells.cnn/index.html