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Reply #15: Package insert: Gardasil has Aluminum, Yeast, Borax & Polysorbate [View All]

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WillYourVoteBCounted Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Aug-08-08 12:15 PM
Response to Reply #13
15. Package insert: Gardasil has Aluminum, Yeast, Borax & Polysorbate
Package insert was Ingredients in Gardasil include Yeast & Borax and Polysorbate .. Polysorbate can cause allergic reactions as well.

Package Insert


GARDASIL * is a non-infectious recombinant, quadrivalent vaccine prepared from the highly purified
virus-like particles (VLPs) of the major capsid (L1) protein of HPV Types 6, 11, 16, and 18. The L1
proteins are produced by separate fermentations in recombinant Saccharomyces cerevisiae and selfassembled into VLPs. The fermentation process involves growth of S. cerevisiae on chemically-defined fermentation media which include vitamins, amino acids, mineral salts, and carbohydrates.

The VLPs are released from the yeast cells by cell disruption and purified by a series of chemical and physical methods.

The purified VLPs are adsorbed on preformed aluminum-containing adjuvant (amorphous aluminum
hydroxyphosphate sulfate). The quadrivalent HPV VLP vaccine is a sterile liquid suspension that is
prepared by combining the adsorbed VLPs of each HPV type and additional amounts of the aluminum containingadjuvant and the final purification buffer.

GARDASIL is a sterile preparation for intramuscular administration. Each 0.5-mL dose contains
approximately 20 mcg of HPV 6 L1 protein, 40 mcg of HPV 11 L1 protein, 40 mcg of HPV 16 L1 protein,
and 20 mcg of HPV 18 L1 protein.

Each 0.5-mL dose of the vaccine contains approximately 225 mcg of aluminum (as amorphous
aluminum hydroxyphosphate sulfate adjuvant), 9.56 mg of sodium chloride, 0.78 mg of L-histidine,
50 mcg of polysorbate 80, 35 mcg of sodium borate, and water for injection. The product does not containa preservative or antibiotics.

After thorough agitation, GARDASIL is a white, cloudy liquid


in "multiple medical preparations (eg, vitamin oils, vaccines, and anticancer agents) "
"Polysorbate 80 is a ubiquitously used solubilizing agent that can cause severe
nonimmunologic anaphylactoid reactions. " \;jsessionid=1oas93idk52v4.victoria
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