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Reply #33: Also, DSM IV was put together in the early 90's [View All]

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depakid Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Apr-20-06 10:08 PM
Response to Reply #28
33. Also, DSM IV was put together in the early 90's
Edited on Thu Apr-20-06 10:15 PM by depakid
so the diagnostic criteria and coding have been through a ton of clinical practice and criticism. If it weren't for the ongoing (and tedious and political) process for DSM V, this would hardly be a story worth printing at this point.

Healy's an interesting fellow. A couple of years ago during the Paxil hearings (where the FDA suppressed their own lead researcher's meta-analysis and banned his testimony) Healy sent an extensive letter outlining his findings re: increased incidence of suicide in adolescent and pediatric patients. It was on the web at the time- and it just slammed the pharmaceutical industry and the agency. Apparently, the MHRA was more receptive (and as I recall halted pediatric use of paxil about 8 months earlier).

His latest barbs at the drug companies look like they are aimed backhandedly at proponents of bipolar spectrum and expanded subtypes- guys like Kleman and Akiskal. He disputes the most recent prevalence figures of around 5%.

Personally, I think he's incorrect, but here's a quick article that shows where he's coming from:

Drug firms encourage manic depression, says academic

Drug companies are in danger of creating an epidemic of bipolar disorder (manic depressive illness) in order to boost sales of mood stabiliser drugs, an academic from Cardiff University will argue at a conference this week. Professor David Healy, Director of the School of Medicine's North Wales sub-department of Psychological Medicine will present his paper The Latest Mania: selling bi-polar disorder, at an inaugural conference on Disease Mongering at the Royal Newcastle Hospital, Australia.

Bipolar disorder is characterised by moods that alternate between two emotional extremes, or poles. Professor Healy acknowledges that bipolar disorder is one of the most debilitating and serious psychiatric diseases but he stresses that the disorder may be described as rare, affecting 0.1 per cent of the world population, with an incidence of about 10 per million of the population.

Professor Healy said: "No drug company is going to be interested in bipolar disorder, unless the prevalence of the disorder can be greatly increased. Since 1980 when the term first entered the Diagnostic and Statistical Manual of Mental Disorders, various forms of bipolar have emerged, and in recent years bipolar prevalence has been pitched as high as 5 per cent of the population.

"Adverts that encourage mood watching risk transforming variations from an emotional even keel into potential indicators of latent or actual bipolar disorder."
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