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In reply to the discussion: My son has autism [View all]MADem
(135,425 posts)8. Sheila, I don't know if you've seen this study out of Yale but it might be worth looking into.
I don't know where they're at on the clinical trials, but if your child is interested they should be able to tell you if/where they're firing them up.
http://news.yale.edu/2014/06/19/hairless-man-arthritis-drug-spurs-hair-growth-lots-it
The patient had previously been diagnosed with both alopecia universalis, a disease that results in loss of all body hair, and plaque psoriasis, a condition characterized by scaly red areas of skin. The only hair on his body was within the psoriasis plaques on his head. He was referred to Yale Dermatology for treatment of the psoriasis. The alopecia universalis had never been treated.
King believed it might be possible to address both diseases simultaneously using an existing FDA-approved drug for rheumatoid arthritis called tofacitinib citrate. The drug had been used successfully for treatingpsoriasis in humans. It had also reversed alopecia areata, a less extreme form of alopecia, in mice.
There are no good options for long-term treatment of alopecia universalis, said King, a clinician interested in the treatment of rare but devastating skin diseases. The best available science suggested this might work, and it has.
After two months on tofacitinib at 10 mg daily, the patients psoriasis showed some improvement, and the man had grown scalp and facial hair the first hair hed grown there in seven years. After three more months of therapy at 15 mg daily, the patient had completely regrown scalp hair and also had clearly visible eyebrows, eyelashes, and facial hair, as well as armpit and other hair, the doctors said.
By eight months there was full regrowth of hair, ... King has submitted a proposal for a clinical trial involving a cream form of tofacitinib as a treatment for alopecia areata.
King believed it might be possible to address both diseases simultaneously using an existing FDA-approved drug for rheumatoid arthritis called tofacitinib citrate. The drug had been used successfully for treatingpsoriasis in humans. It had also reversed alopecia areata, a less extreme form of alopecia, in mice.
There are no good options for long-term treatment of alopecia universalis, said King, a clinician interested in the treatment of rare but devastating skin diseases. The best available science suggested this might work, and it has.
After two months on tofacitinib at 10 mg daily, the patients psoriasis showed some improvement, and the man had grown scalp and facial hair the first hair hed grown there in seven years. After three more months of therapy at 15 mg daily, the patient had completely regrown scalp hair and also had clearly visible eyebrows, eyelashes, and facial hair, as well as armpit and other hair, the doctors said.
By eight months there was full regrowth of hair, ... King has submitted a proposal for a clinical trial involving a cream form of tofacitinib as a treatment for alopecia areata.
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I do understand that part about parents will do anything to make sense or try to find a cure.
SheilaT
Sep 2014
#3
Sheila, I don't know if you've seen this study out of Yale but it might be worth looking into.
MADem
Sep 2014
#8
I sent that to my mother-in-law (who has alopecia universalis) a few weeks ago.
deurbano
Sep 2014
#17
It does look very hopeful--the question will be if the results are translatable over a wide swathe
MADem
Sep 2014
#20
My stepson is autistic and my son has some autistic traits, so I undersand what you
1monster
Sep 2014
#6
I refuse to stand in judgement of parents that have children with severe autism.
liberal_at_heart
Sep 2014
#16
Just waiting for Tn. to legalize it and a brave enough doctor to prescribe it.
Separation
Sep 2014
#31
Why do you conflate "anti-vax crowd" with people who advocate for vaccine SAFETY?
pnwmom
Sep 2014
#26
"Most people." That doesn't help the people who are injured -- like my sister who was killed --
pnwmom
Sep 2014
#35
No, the standard should be as safe as possible, not just "most." And that wasn't the case with the
pnwmom
Sep 2014
#37