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Tue Jun 8, 2021, 07:23 AM

Researchers create new optical biosensor to detect cancer

Shane McGlaun - Jun 8, 2021, 5:23am CDT

Biosensors are important diagnostic devices that have to be quick, cheap, and easy to use. It’s also beneficial if biosensors are compact and autonomous so they can be used by anyone from doctors down to the patient themselves. Most optical biosensors require a wide range of light colors, like a rainbow, to operate reliably.

The need for a wide range of light makes the sensors bulky, expensive, and more sophisticated. Most biosensors available today require a spectrometer to extract the most precise data from each light color, limiting their use. Scientists at EPFL have introduced a new concept that allows a single light color to operate as a simple imaging detector. Despite using only a single color of light, the system provides extremely accurate bio-sensing information as if the entire rainbow of light colors illuminated the sensor.

The new biosensor uses two specific functions including nanophotonics and data science techniques. The chips themselves are constructed out of nanostructures made from silicon. Nanostructure silicon surfaces have features in the order of 100 nm to trap light on the biosample/chip interface more efficiently. That makes biosensors extremely sensitive to the presence of biomarkers resulting in distinct changes in incident light features.

That feature is the change in the “amount” of collected light known as light intensity. Typically, the camera continuously receives the light that passes through the biochip to acquire images from the biochip with intensity information over millions of image pixels. Biomarkers attached to the nanostructures on the biochip and intensity change images are compiled from the induced intensity change of each pixel at very high resolutions.


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Reply Researchers create new optical biosensor to detect cancer (Original post)
Judi Lynn Jun 8 OP
rampartc Jun 8 #1

Response to Judi Lynn (Original post)

Tue Jun 8, 2021, 10:43 AM

1. very interesting.

i'll bring this to my oncologist's attention.

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