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Thu Jun 10, 2021, 02:57 AM

Nitrous oxide, or "laughing gas", rapidly relieves severe depression

https://newatlas.com/health-wellbeing/nitrous-oxide-severe-depression-phase2-study-results/
"
A Phase 2 clinical trial has found a 60-minute treatment session with the gas nitrous oxide can deliver significant and rapid improvements in patients with treatment-resistant depression, and the research indicates these benefits can last for at least two weeks."
"An early proof of concept trial offered compelling clues the gas could indeed rapidly relieve symptoms of depression. Subsequent preliminary research suggested the gas could also potentially treat post-traumatic stress disorder (PTSD) and alcoholism.

This new study set out to investigate whether lower doses of nitrous oxide than previously tested were effective for depression, and whether the benefits from a single treatment last for several weeks. Each of the 24 subjects recruited for the trial completed three treatment sessions, each one hour long, spaced a month apart. Alongside a placebo session breathing only oxygen, the subjects tested 25 percent and 50 percent nitrous oxide concentrations.
The researchers found 85 percent of the subjects showed significant improvements to their depression symptoms after a single nitrous oxide treatment and, most importantly, the lower dose was almost as effective as the higher dose but with substantially fewer negative side effects."

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Reply Nitrous oxide, or "laughing gas", rapidly relieves severe depression (Original post)
CentralMass Jun 10 OP
Buckeye_Democrat Jun 10 #1
CentralMass Jun 10 #3
Buckeye_Democrat Jun 10 #4
CentralMass Jun 10 #5
Buckeye_Democrat Jun 10 #6
CentralMass Jun 10 #2
SleeplessinSoCal Jun 10 #7
multigraincracker Jun 10 #8
Rhiannon12866 Jun 10 #9
madamesilverspurs Jun 10 #10

Response to CentralMass (Original post)

Thu Jun 10, 2021, 03:06 AM

1. Interesting.

Doubt it would help me, given how it never worked for me when I had an old "implant" removed by an oral surgeon.

The old guy eventually shook his head, after it was turned up to the maximum setting and I was still inhaling deeply, and he said something like, "Oh, dear. You're clearly one of those rare people unaffected by it."

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Response to Buckeye_Democrat (Reply #1)

Thu Jun 10, 2021, 03:14 AM

3. I haven't had it in many years but I have a similar constitution

when it comes to "getting put under"

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Response to CentralMass (Reply #3)

Thu Jun 10, 2021, 03:24 AM

4. Other types of anesthesia has worked fast on me.

Like during a couple of past hernia operations. I reacted pretty strongly to them, actually, with doctors and nurses being very concerned about my extremely low blood pressure afterwards. Stupid me, I should've recorded whatever they used each of those times to avoid them in the future.

The last time, I remember feeling GREAT when the screaming from a female nurse finally got through to me. It was like a movie scene during a loud battle (but blissful), with another soldier's yelling being barely heard until the volume gradually increased to full-blast. Then I briefly opened my eyes, and closed them again since I wanted to get back to those super-pleasant feelings. At which point she started shaking me and demanded that I not fall asleep.

I'm still an atheist despite that incredible experience. Lol.

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Response to Buckeye_Democrat (Reply #4)

Thu Jun 10, 2021, 03:38 AM

5. Lol. I am slow to go under but typically recover poorly from being under.

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Response to CentralMass (Reply #5)

Thu Jun 10, 2021, 03:50 AM

6. Yeah, the recovery from my past surgeries...

... were very slow, at least from what I was told.

I could barely keep my head from flopping over when the hospital staff finally put me in a wheelchair to get me the heck out of there, after the first operation. I was thinking at the time, "I'm still so weak that my muscles don't seem to be working, and you're rolling me out of here already? Was there a mass shooting around here or something, with the need for more hospital beds?" But they insisted that I should've felt fully recovered long ago, so away I went!

The second time, with the screaming nurse, was at a different hospital. They were a bit extreme the other way, not releasing me for several more hours to a niece (who was there to drive me home) even after I told them I was totally fine now.

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Response to CentralMass (Original post)

Thu Jun 10, 2021, 03:11 AM

2. No Lindsey, that was "laughing" gas.

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Response to CentralMass (Original post)

Thu Jun 10, 2021, 03:53 AM

7. I ask my dentist for laughing gas, and she just laughs.

If it relieves depression, I'm going to keeping asking for it.

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Response to CentralMass (Original post)

Thu Jun 10, 2021, 04:23 AM

8. Sorry, I didn't hear you. I have this ringing in my ears.

I found some Whippets and a ballon.

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Response to CentralMass (Original post)

Thu Jun 10, 2021, 04:52 AM

9. Where do I get some??

I think a lot of us could use some of that these days!

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Response to CentralMass (Original post)

Thu Jun 10, 2021, 04:59 AM

10. Not for everyone.

Me, f'rinstance.

Seems I'm one of those whose response to meds is sometimes bassackwards, nitrous oxide being one case. Scared the crap out of the dentist, I was sobbing so loudly they had to put me in a room at the back of the offices with the door closed, seems I was scaring the patients in the waiting room.

Then there's benedryl, has me bouncing off the walls . . .


.

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