Nicotine being tested for Covid-19 treatment. More woo?
Nicotine really makes a nice insecticide barrier for my raspberries and other vulnerable plants in my garden. I won't use any chemical out here so I'm always trying organic home methods.
Are smokers really being infected at a lower rate? Accurate information comes as a rarity these days.
Do you have any context or references to offer on that? Links are also useful.
Well, I think of The Guardian as a reasonable source, comparatively.
It is the clinical trials aspect that is important here. The data suggests the possibility, but at this point it is speculative.
Smokers are reported as having a higher risk of serious cases of CoViD-19, but I see this:
French researchers to test nicotine patches on coronavirus patients
Study which stresses serious health risks of smoking suggest substance in tobacco may lower risk of getting coronavirus
French researchers are planning to test nicotine patches on coronavirus patients and frontline health workers after a study suggested smokers may be much less at risk of contracting the virus.
The study at a major Paris hospital suggests a substance in tobacco possibly nicotine may be stopping patients who smoke from catching Covid-19. Clinical trials of nicotine patches are awaiting the approval of the countrys health authorities.
However, the researchers insisted they were not encouraging the population to take up smoking, which carries other potentially fatal health risks and kills 50% of those who take it up. While nicotine may protect those from the virus, smokers who have caught it often develop more serious symptoms because of the toxic effect of tobacco smoke on the lungs, they say.
The team at Pitié-Salpêtrière hospital questioned 480 patients who tested positive for the virus, 350 of whom were hospitalised while the rest with less serious symptoms were allowed home.
It found that of those admitted to hospital, whose median age was 65, only 4.4% were regular smokers. Among those released home, with a median age of 44, 5.3% smoked.
in cigarettes that causes major health issues and the propensity for greater lung infections.
Nicotine in its pure form, dissociated from tobacco smoking, does not seem to cause heart attacks or strokes. But as a powerful vasoconstrictor, it can reduce gas exchange in the lungs, and over time, can cause chronic microvascular ischemic changes in the brain, which can lead to memory loss. Also, as a stimulant, it can disrupt the user's circadian rhythm, leading to sleep deficit and the cognitive changes that come with it.
Nicotine users can come up with many excuses to not quit nicotine use, and this one is growing in popularity. But it is misleading to a significant extent.
That can't be good.
I quit the cancer sticks, now I'll be tapering off the gum.
I tell my patients that, as good for your physical health quitting cold turkey would be, it is a nightmare for your psychological health. It's the biggest reason why smokers fail to quit.
I always tell them to taper off slowly. This not only reduces your tolerance and dependence on nicotine in a bearable way, it also decreases the psychological need to go digging around for the pack, and the ritual of lighting up.
It would be fascinating to get real numbers when the French study is completed.
Just because it is organic does not mean it isn't a toxic chemical pesticide.
Well, I mean physically exists ... water, air, us, everything.
Maybe something like dark matter isn't a chemical, and theoretically 'exists' but ... almost everything.
But you're right about concentrated nicotine, it is highly toxic.
To your point, it's kinda like just because morphine is a naturally occurring substance doesn't mean it's not addictive and can't kill you through overdose.
A substance being naturally-occurring (or conversely, not) has absolutely no relevance to its safety profile.
Nicotine more than most, but rotenone and pyrethrin also have high mammalian toxicity. Neem is fairly safe but exposure is not recommended for pregnant women. Unfortunately there is a lot of "if it is naturally occuring it is safe." I guess people have not heard of poison frogs, ricin from castor beans, atropine, etc.
Not nicotine. Holy cow thanks for pointing that out. My bad.
access to a quality ventilator. The ventilator is very useful fighting severe pneumonia. I speak from first hand experience watching my wife in coma from double pneumonia was placed on a ventilator in ICU for several days and she eventually recovered fully! Without the ventilator forcing air in her lungs she had no chance.
So good to see USA now has surplus ventilators and is now helping Mexico, Spain, France, Italy with surplus ventilators.
... other risk factors for Covid-19 like hypertension, obesity and diabetes.
Asthma doesnt seem to be nearly as risky as previously thought, according to the recent study from New York.
I would be SHOCKED if smoking actually helped, though.
I've been observing the NY state statistics, but hadn't seen the study WRT asthma. My mom is 85 and has asthma, so it's important to me.
I was getting ready to log off.
Yeah, heres the Washington Post link and text.
The paper also found that of those who were hospitalized, 57 percent had hypertension, 41 percent were obese and 34 percent had diabetes which is consistent with risk factors listed by the Centers for Disease for Control and Prevention. Noticeably absent from the top of the list was asthma. As doctors and researchers have learned more about covid-19, the less it seems that asthma plays a dominant role in outcomes.
Any compromise to the health of the lungs is going to make COVID-19 more difficult to survive.
There is nothing you can have that can't be made worse by smoking, and nothing you can have that can't be made better by quitting.
one paper I don't want to pay to access:
S1932 Effect of Nicotine On Innate Antiviral Pathways and HCV Replication
Yamashina et al., 2008
(Sorry, this link keeps posting as a broken link)
Supposedly the study asserts nicotine prevents Hepatitis C viral replication.
Doubt much will come of this, but we'll see. The xylitol in Nicorette also does some interesting things.
Perhaps blood pressure, anticlotting, gas transfer, or something completely different.
I'd assume replication's the least likely--like preventing attachment of the virion to a cell and injection of the RNA, that's a pretty small target.
I was setting up my nebulizer.
(Good thing I did not quit because of the virus but cause was hard to breathe sometimes and coughin' and rattlin', lol).
How are you supposed to fight a lung disease if your lungs are fried from tobacco smoke? This doesn't make a whole lot of sense.