Democratic Underground Latest Greatest Lobby Journals Search Options Help Login
Google

They're calling for volunteers for the clinical trial of my drug!

Printer-friendly format Printer-friendly format
Printer-friendly format Email this thread to a friend
Printer-friendly format Bookmark this thread
This topic is archived.
Home » Discuss » Archives » General Discussion (01/01/06 through 01/22/2007) Donate to DU
 
Th1onein Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 09:43 PM
Original message
They're calling for volunteers for the clinical trial of my drug!
I am so excited. And scared. My work is going to be tested.

I never thought I'd get this far, but here we are! If my model is correct, I will have stopped one of the most common genetic killers of children in this country. If I'm wrong, it's back to the drawing board.

It seems almost surreal to me, at this point, to see the call for volunteers.
Printer Friendly | Permalink |  | Top
MadMaddie Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 09:44 PM
Response to Original message
1. Congrats my DU friend....and good luck....
:applause:
Printer Friendly | Permalink |  | Top
 
Downtown Hound Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 09:45 PM
Response to Original message
2. Wow! Good luck!
It must feel really good to have gotten this far. I understand that's not easy in that industry.
Printer Friendly | Permalink |  | Top
 
JeffR Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 09:46 PM
Response to Original message
3. Keeping my fingers crossed for ya!
:toast:

Printer Friendly | Permalink |  | Top
 
Cameron27 Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 09:46 PM
Response to Original message
4. How amazing!
Congratulations and good luck.
Printer Friendly | Permalink |  | Top
 
Old and In the Way Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 09:47 PM
Response to Original message
5. Wow, that is really interesting.
I admire anyone whose knowledge of chemistry and biology works at this level. Good luck, maybe they'll be a Nobel Prize in your future!
Printer Friendly | Permalink |  | Top
 
Th1onein Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 09:58 PM
Response to Reply #5
10. I very much doubt any prizes are coming my way
I'm a "non-professional scientist." I got into this because my son had cystic fibrosis and I was fighting for his life. That was eleven years ago. After he died, eight years ago, I just couldn't stop studying. A group of parents on a CF support group heard about the work and they decided to support it. These people didn't just form a non-profit and raise funds; they never quit and they never let me quit. They never gave up and they never let me give up. And here we are. It just goes to show you what people, joined together for a common purpose, can do.

I don't deserve any prize. This group of people who came together in love, with a fighting spirit and a common cause, deserve all of the prizes.
Printer Friendly | Permalink |  | Top
 
Catherine Vincent Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 10:16 PM
Response to Reply #10
17. Wow! That is very commendable of you.
Congratulations! And I hope your testing is a success!
Printer Friendly | Permalink |  | Top
 
Old and In the Way Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 11:39 PM
Response to Reply #10
33. Even more amazing......I'm so sorry about your son, but I can understand
your motivation to find a cure. I truly hope your work is sucessful, it will be a gift to millions and provide you some comfort in your personal loss. What a story of inspiration. Thanks for posting about this.
Printer Friendly | Permalink |  | Top
 
malaise Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Oct-13-06 05:38 AM
Response to Reply #10
43. Nice start to my day
:yourock:
Printer Friendly | Permalink |  | Top
 
Horse with no Name Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Oct-13-06 05:06 PM
Response to Reply #10
54. Awesome.
A friend of mine lost her son when he was 7 to CF.
Thank you for your great work.
Printer Friendly | Permalink |  | Top
 
KoKo Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Oct-13-06 10:18 PM
Response to Reply #10
64. Great to hear! Thanks for the news!
:applause:
Printer Friendly | Permalink |  | Top
 
livetohike Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 09:47 PM
Response to Original message
6. Congratulations and Way to Go!
:thumbsup: Looking forward to hearing more positive news from you on this :-).
Printer Friendly | Permalink |  | Top
 
catnhatnh Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 09:47 PM
Response to Original message
7. What is your disease?
I had two nephews killed by a form of MD passed only to male heirs (I forget the exact term) and since they were the first boys in two generations.....I always hoped to see that bitch whipped in my lifetime....
Printer Friendly | Permalink |  | Top
 
gully Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 10:13 PM
Response to Reply #7
16. See post 10
Cystic Fibrosis
Printer Friendly | Permalink |  | Top
 
Th1onein Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 11:08 PM
Response to Reply #7
30. Your disease was Duchenne's Muscular Dystrophy?
It is carried on the X chromosome, so most females with the disease have a functional form of the protein. Males are not so lucky. Duchenne's is a particularly cruel disease. The last I read about it, though, they were very close to doing something very radical to change the outcome for these children. I don't know that they will, though, unless some "radical" parents get together and make sure that this research is followed out to it's logical end.
Printer Friendly | Permalink |  | Top
 
catnhatnh Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 11:25 PM
Response to Reply #30
32. That was the name...
I cannot follow it too closely...I do what I can for fundraising and hope it is given proper gravity....If I give X dollars towards MD, would it not seem somehow cheap to name which form was my aim?
Printer Friendly | Permalink |  | Top
 
Th1onein Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Oct-13-06 07:41 AM
Response to Reply #32
44. It is the deadliest form of the disease.
The other forms don't kill as rapidly as Duchenne's.
Printer Friendly | Permalink |  | Top
 
shance Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 09:48 PM
Response to Original message
8. That's exciting Th1*** Congratulations!
Good luck - may many blessings come your way!
Printer Friendly | Permalink |  | Top
 
catnhatnh Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 09:48 PM
Response to Original message
9. Oh-and congratulations...
...and fingers crossed for all of us...
Printer Friendly | Permalink |  | Top
 
librechik Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 10:01 PM
Response to Original message
11. Cool--what a great feeling that must be
enjoy and thanks for your dedication!

NGU!
Printer Friendly | Permalink |  | Top
 
catnhatnh Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 10:05 PM
Response to Original message
12. And a last thought...
...you know the odds and the statistics.You have done your best and the world wishes you well-ain't no one hoping against you. You are what this world needs whether this attempt is a success or not.There is no youthful killer that doesn't deserve and need you and others like you.So you walked to the plate and swung-I pray you hit it out of the park.If not there are other pitches and other swings....Go,Baby....
Printer Friendly | Permalink |  | Top
 
Th1onein Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 10:24 PM
Response to Reply #12
21. What an absolutely lovely thing to write, catnhatnh
I'm scared. And very tired. Eleven years of work is a long time.

But, you know, if I don't hit it out of the park this time, my butt will be back on the practice field the next morning, trying to figure out where I went wrong. I've gone too far to turn back now.
Printer Friendly | Permalink |  | Top
 
catnhatnh Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 10:50 PM
Response to Reply #21
29. Darling....
...I watched my brother-a much better man than I-and my sister-in-law (a double saint for her love of the boys and her tolerance of my brother) lose their kids-and so have you-life can kick you again but never that hard...eleven years IS a long time-guess who smiles on and blesses your work tonight-no matter the outcome???This is your Taj Mahal-a labor, an homage to your love-and love is never lost or poured down a blind hole....I pray it works, but your love is pure and perfect.God Bless those who drive too fast into a turn-because if they pull it off, they are superstars and if they don't their inspiration is special...Regards,Cat
Printer Friendly | Permalink |  | Top
 
Canuckistanian Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 10:07 PM
Response to Original message
13. You've been having quite a year
First your sister and now this.

Karma works in stange ways....

Congrats!
:toast:
Printer Friendly | Permalink |  | Top
 
SlavesandBulldozers Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 10:12 PM
Response to Original message
14. wicked.
congratulations are already in order no matter the outcome. I admire your focus and drive and wish you all the best. You certainly deserve it!
Printer Friendly | Permalink |  | Top
 
benddem Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 10:12 PM
Response to Original message
15. the fact it is going to go to clinical trial
is amazing..and many congratulations. I will keep my fingers crossed for you and all the cystic fibrosis kids now and in the future. :toast: :grouphug:
Printer Friendly | Permalink |  | Top
 
lumberjack_jeff Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 10:18 PM
Response to Original message
18. I just read Sex, Drugs and DNA
Apparently the percentage of researchers who EVER make a drug which actually goes to clinical trial is very small.

Congratulations!
Printer Friendly | Permalink |  | Top
 
stevedeshazer Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 10:20 PM
Response to Original message
19. Wonderful
:hug:

The world needs more of that.
Printer Friendly | Permalink |  | Top
 
mmonk Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 10:23 PM
Response to Original message
20. Pulling for your success.
My fingers are crossed.
Printer Friendly | Permalink |  | Top
 
HeeBGBz Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 10:25 PM
Response to Original message
22. Well, WTG, Th1onein, I wish you the best possibilities!
"I want a new drug
One that does what it should
One that wont make me feel too bad
One that wont make me feel too good"



Printer Friendly | Permalink |  | Top
 
Lars39 Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 10:25 PM
Response to Original message
23. I remember your story!
Just reading it was mind boggling! I hope all goes very, very well. :hug:
Printer Friendly | Permalink |  | Top
 
G Hawes Donating Member (440 posts) Send PM | Profile | Ignore Thu Oct-12-06 10:25 PM
Response to Original message
24. Best of luck to you, Th1onein
And great big kudos to you on your work, your passion, and your perserverance.

Printer Friendly | Permalink |  | Top
 
Control-Z Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 10:42 PM
Response to Original message
25. Oh, wow!
That is an enormous accomplishment.

It must have taken amazing strength - to work so hard - to persevere.

I wish you the very best in those trials.

Printer Friendly | Permalink |  | Top
 
driver8 Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 10:44 PM
Response to Original message
26. A big congratulations to you !!
That is really amazing! What a story...
Printer Friendly | Permalink |  | Top
 
Kurovski Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 10:46 PM
Response to Original message
27. Best of luck, and thank you!
Recommended.
Printer Friendly | Permalink |  | Top
 
dave502d Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 10:47 PM
Response to Original message
28. Good luck and thank you. n/t
Printer Friendly | Permalink |  | Top
 
sandnsea Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 11:13 PM
Response to Original message
31. Wow!! Congratulations!
Edited on Thu Oct-12-06 11:13 PM by sandnsea
Is there another "Lorenzo's Oil" in the works perhaps?? You have a fascinating and inspiring story. I sure hope the medicine is successful and helps lots of kids. Congratulations again!

:applause:
Printer Friendly | Permalink |  | Top
 
TygrBright Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 11:53 PM
Response to Original message
34. Wow. Just... Wow.
Thank you.

People like you give me hope. I remember reading about Jonas Salk when I was a youngster, and how he refused to patent his vaccine because he wanted every kid to be able to live free of the horror of polio. There were still kids who had survived polio in school with me; it was a very real threat.

I read "The Microbe Hunters," and thought that there was nothing more exciting and heroic than the men and women in laboratories, working to free humanity from the fear and suffering of terrible diseases.

But by the time I grew up, it was all about "money pills"-- Big Pharma had consolidated everything into a machine diligently searching for profits, working on yet another cure for acid indigestion or male pattern baldness or weight gain or erectile dysfunction. "Researchers" would make their latest "discoveries" by making one minute molecular change or addition to some compound so they could take out a new patent. Drug companies were refusing to manufacture and distribute life-saving vaccines because there wasn't enough profit in it. Holding dying AIDS patients and health care systems in poverty-stricken countries hostage for vast profits on hypercostly medicines.

It seemed like there were no more of the white-coated lab warriors tackling the toughest, cruelest diseases because they BELIEVED in a cure, believed in the importance of the work, even if it wouldn't make a huge profit.

Thank you for restoring my faith. My prayers are with you and the clinicians managing the trials.

appreciatively,
Bright
Printer Friendly | Permalink |  | Top
 
Bridget Burke Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Oct-13-06 08:42 AM
Response to Reply #34
49. The "white coated lab warriors" never went away.
But the "suits" decide what deserves funding. Most of the time, that is.

Printer Friendly | Permalink |  | Top
 
shadowknows69 Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Oct-12-06 11:54 PM
Response to Original message
35. If this succeeds
would you consider designing a drug that eliminates the genetic predisoposition to become a republican?
Printer Friendly | Permalink |  | Top
 
Diane R Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Oct-13-06 12:46 AM
Response to Original message
36. Bless you.
I know a wonderful little girl with CF who desperately needs a cure. And, I know a girl who died when she was only 20 years old.

Crossing all my fingers, toes and eyeballs that this trial will work. But even if it doesn't, you've helped everyone move closer to a cure.
Printer Friendly | Permalink |  | Top
 
Th1onein Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Oct-13-06 08:29 AM
Response to Reply #36
45. We should know the results in three or four months.
We had a carrier (a parent) who took it upon himself to test this drug on himself and the results were amazing. It is, without a doubt, one of the most satisfying feelings in the world, to go from a theory on paper, to the lab, and to see it bear out. You can be as sure of your theory as is humanly possible and still be absolutely shocked at the results of testing it, especially when the outcome is so dramatic.

I don't know if it will work in CF patients, themselves, though. Or even if it manages to change one of the major pathological indices in this disease, if it will change the overall pathology of the disease. It is going to be difficult to wait and see. Thank God I have my day job to keep me busy.
Printer Friendly | Permalink |  | Top
 
DeepModem Mom Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Oct-13-06 12:56 AM
Response to Original message
37. My daughter lost a very close friend, an extraordinary girl...
she'd known since early childhood to CF not too long ago. I pray your efforts succeed, and I thank you.
Printer Friendly | Permalink |  | Top
 
pitohui Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Oct-13-06 12:58 AM
Response to Original message
38. go you and good luck
there would be no need for tests if we knew everything in advance

you are trying, that's what counts, take it a day at a time
Printer Friendly | Permalink |  | Top
 
BlooInBloo Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Oct-13-06 01:05 AM
Response to Original message
39. How exciting! Congratulations!!! Good luck!
Printer Friendly | Permalink |  | Top
 
RevolutionStartsNow Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Oct-13-06 01:05 AM
Response to Original message
40. Amazing story.
Beautiful. Your compassion and determination is so admirable.

Keep pushing!

Printer Friendly | Permalink |  | Top
 
KT2000 Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Oct-13-06 01:55 AM
Response to Original message
41. This is great!!
All I can say is
:bounce: :yourock: :applause:
Printer Friendly | Permalink |  | Top
 
lostnfound Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Oct-13-06 05:35 AM
Response to Original message
42. We are excited for you!!!
How proud you should be. I deeply hope it is a big success.
Printer Friendly | Permalink |  | Top
 
AzDar Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Oct-13-06 08:32 AM
Response to Original message
46. That is fantastic! All the best....n/t
Printer Friendly | Permalink |  | Top
 
knitter4democracy Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Oct-13-06 08:36 AM
Response to Original message
47. That's great!!!
You'll find out so much more in the testing phase. You'll see how it really works in real life, and you just can't duplicate that in a lab. I'm so happy for you! That's a drug that we need.
Printer Friendly | Permalink |  | Top
 
myrna minx Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Oct-13-06 08:39 AM
Response to Original message
48. Your extraordinary work has truly honored your
child's memory.
Printer Friendly | Permalink |  | Top
 
IdaBriggs Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Oct-13-06 03:07 PM
Response to Original message
50. Yeah! You Rock! Congratulations!
:yourock: :woohoo: :bounce: :toast: :yourock: :woohoo: :bounce: :toast: :yourock: :woohoo: :bounce: :toast: :yourock: :woohoo: :bounce: :toast: :yourock: :woohoo: :bounce: :toast: :yourock: :woohoo: :bounce: :toast:
Printer Friendly | Permalink |  | Top
 
Richard Steele Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Oct-13-06 03:12 PM
Response to Original message
51. I hope it tests well, Th1onein! nm
Printer Friendly | Permalink |  | Top
 
Avalux Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Oct-13-06 03:13 PM
Response to Original message
52. Phase I trials?
I'm assuming you've already done animal models with good results. I'd be interested in knowing more about your compound. :hi:
Printer Friendly | Permalink |  | Top
 
Th1onein Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Oct-13-06 05:04 PM
Response to Reply #52
53. We didn't have to do an animal model
It is a compound that comes from a food, so we didn't have to do that. We are testing directly on the patients, themselves. The compound is benzyl isothiocyanate, which comes from papaya seeds.
Printer Friendly | Permalink |  | Top
 
civildisoBDence Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Oct-13-06 05:11 PM
Response to Reply #53
56. Regardless of the outcome of the clinincal trials,
you've forwarded the science on CF.

Congratulations--may more be in the offing!

Newsprism
Printer Friendly | Permalink |  | Top
 
Avalux Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Oct-13-06 05:30 PM
Response to Reply #53
57. Thanks for the info.
I wish you the best of luck - please keep us posted on your progress. :hug:
Printer Friendly | Permalink |  | Top
 
Fleshdancer Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Oct-13-06 05:07 PM
Response to Original message
55. WOW! please please PLEASE keep us updated!
Edited on Fri Oct-13-06 05:09 PM by GloriaSmith
may I ask what genetic killer you're refering to?

on edit: nevermind...I read more of the thread. :D Your story has me tearing up. :hug:
Printer Friendly | Permalink |  | Top
 
Mnemosyne Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Oct-13-06 06:00 PM
Response to Original message
58. How exciting Th1onein! My nephew died at 8 months of
global genetic defects. I know how much this means.

:yourock:
Printer Friendly | Permalink |  | Top
 
brook Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Oct-13-06 06:12 PM
Response to Original message
59. what a compelling
story. To read what you have chosen to do after such a tragedy as losing your precious child is awe-inspiring.
May the deities bless you and this trial.
Printer Friendly | Permalink |  | Top
 
wiley Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Oct-13-06 06:31 PM
Response to Original message
60. This compound has been studied in animals and humans for at least 30 years
Herbs and fruits and vegetables that contain this compound have been used by healers for centuries. The US Army Survival Manual mentions severasl sources of this compound for certain illnesses (mainly helminths). Please explain what you mean by your model. Is it based on eating papaya seeds over a certain period of time, or a pill taken x number of times a day, or an on one week off several months infusion of benzyl isothiocyanate.

Would you please provide a link to either a protocol description of the clinical trial you are talking about that is recruiting, or at least the Informed Consent for this study? Is the protocol rationalization based on BITC as a mechanism-based inactivator of various forms of P450s? Just a little bit more info, please? Published papers?
Printer Friendly | Permalink |  | Top
 
Th1onein Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Oct-13-06 10:13 PM
Response to Reply #60
62. I don't have the protocol on this computer; sorry.
And I'm not sure that it is available to the public yet. The IRB has it, though. As well as the informed consent. No, BITC is not used to inactivate any form of P450. It is used to induce a functionally redundant protein (MRP-1) to the CFTR protein, which is mutated in this disease.

You can look up the abstract on PubMed, by searching "Melanie Childers." It's the only abstract that pops up under those search terms.
Printer Friendly | Permalink |  | Top
 
wiley Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Oct-14-06 01:55 AM
Response to Reply #62
65. Thank You. Very Exciting. I pray it works
If so, it could not only address CF, but perhaps serve as a prototype for addressing similar concerns related to drug resistance (not a shabby idea considering MRSA and resistance that develops to otherwise effective drugs), esophageal and lung and or breast cancer, AIDS, etc. I look forward to seeing a protocol perhaps in the future, but first and foremost hope that the first person who takes this drug in whatever formulation leads to a second person and to the completion of a successful Phase I study. That's all and everything that we can hope for. I wish for so many kids that this was a therapy available right now, but we know how research works and why it must be done. Even a small successful proof of concept trial with mixed results could blow the whole field wide open and lead to better treatments for those coming up. Good Luck to us all. May you never tire or lose hope in a despondent hour.
Printer Friendly | Permalink |  | Top
 
nicknameless Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Oct-13-06 07:13 PM
Response to Original message
61. Awesome, Th1onein!
I am so sorry you lost a child to this.
Thank you for never giving up.
Please keep us posted.

Printer Friendly | Permalink |  | Top
 
mrreowwr_kittty Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Oct-13-06 10:15 PM
Response to Original message
63. Well done!
I'm so happy for you. I remember when you posted about your sister passing. I'm glad for this positive development in your life and career and I wish you the best of luck. :hug:
Printer Friendly | Permalink |  | Top
 
DU AdBot (1000+ posts) Click to send private message to this author Click to view 
this author's profile Click to add 
this author to your buddy list Click to add 
this author to your Ignore list Tue Sep 23rd 2014, 07:34 AM
Response to Original message
Advertisements [?]
 Top

Home » Discuss » Archives » General Discussion (01/01/06 through 01/22/2007) Donate to DU

Powered by DCForum+ Version 1.1 Copyright 1997-2002 DCScripts.com
Software has been extensively modified by the DU administrators


Important Notices: By participating on this discussion board, visitors agree to abide by the rules outlined on our Rules page. Messages posted on the Democratic Underground Discussion Forums are the opinions of the individuals who post them, and do not necessarily represent the opinions of Democratic Underground, LLC.

Home  |  Discussion Forums  |  Journals |  Store  |  Donate

About DU  |  Contact Us  |  Privacy Policy

Got a message for Democratic Underground? Click here to send us a message.

© 2001 - 2011 Democratic Underground, LLC