What is "The Big Lie"? Is this a function of genetics?

[Stanchetalarooni]

I have seen reference to "the Big Lie" and have an intuitive sense of what it means but not a literal descriptive sense.
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[valerief]

1. I think it's Original Sin. n/t

[baldguy]

2. Adolf Hitler in Mein Kampf:

Of course, his idea is itself a Big Lie.

The phrase Big Lie refers to a propaganda technique which entered mass consciousness with Adolf Hitler's 1925 autobiography Mein Kampf. In that book Hitler wrote that people came to believe that Germany lost World War I in the field due to a propaganda technique used by Jews who were influential in the German press. This technique, he believed, consisted of telling a lie so "colossal" that no one would believe anyone "could have the impudence to distort the truth so infamously". The first documented use of the phrase "big lie" is in the corresponding passage: "in the big lie there is always a certain force of credibility".

more:
http://en.wikipedia.org/wiki/Big_lie

And the neocons wonder why they are so often compared to Nazis.

[valerief]

3. Naw, he's just fishing to spout some anti-evolution rhetoric.

He's not talking about the real Big Lie of propaganda as you've pointed out.