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Cold sores 'an Alzheimer's risk' (BBC)

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eppur_se_muova Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Dec-08-08 05:31 PM
Original message
Cold sores 'an Alzheimer's risk' (BBC)
Catching a cold sore puts you at risk of Alzheimer's disease, mounting evidence suggests.

The herpes virus behind cold sores is a major cause of the protein plaques that accumulate in the brains of people with Alzheimer's, scientists have shown.

On the plus side, the latest discovery by the University of Manchester team may mean antiviral drugs used to treat cold sores could also prevent dementia.

The findings are published in the Journal of Pathology.

Professor Ruth Itzhaki and colleagues found DNA evidence of the herpes simplex virus (HSV) type 1 in 90% of plaques in Alzheimer's disease patients' brains.
***
more: http://news.bbc.co.uk/2/hi/health/7770680.stm
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Deja Q Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Dec-08-08 05:35 PM
Response to Original message
1. For people to go playing around indiscriminately - they're already brain-dead.
Edited on Mon Dec-08-08 05:36 PM by HypnoToad
:(

(IMHO, of course. There are those who are victims to scumbags who cheat around.)
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drm604 Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Dec-08-08 05:42 PM
Response to Reply #1
2. Cold sores are not a veneral disease.
They certainly can be caught that way but it's far from the only way.
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navarth Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Dec-08-08 05:45 PM
Response to Reply #1
3. I don't get your meaning
My Mom has beginning Alzheimer's and I remember her having cold sores on her lip in earlier years...this is making me wonder about that.

But she didn't mess around. She had four boys to raise, and raise us she did. No extramaritals. How did she get cold sore? I dunno.

I guess I'm just pointing out that we shouldn't assume that cold sores automatically come from promiscuity. If that's what you meant.
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BanzaiBonnie Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Dec-08-08 06:00 PM
Response to Reply #1
8. Excuuuuuuse me
My daughter had her first outbreak when she was about 14. She was mortified as she didn't even date. From what I understand, Herpes is a virus related to chicken pox and shingles. Should we blast all of them by calling them brain-dead?

Sorry Hypno, you're over the brink with this one.
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eppur_se_muova Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Dec-08-08 07:10 PM
Response to Reply #1
12. The term 'herpes' includesa large group of viruses, among them *genital* herpes. nt
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uppityperson Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Dec-08-08 11:20 PM
Response to Reply #1
13. You are showing your ignorance. Here is more info for you, educate yourself please...
http://www.britannica.com/EBchecked/topic/693113/herpes...
infection, of either the skin or the genitalia, caused by either of two strains of the herpes simplex virus. Herpes simplex virus type 1 (HSV-1) is transmitted orally and is responsible for cold sores and fever blisters, typically occurring around the mouth, whereas herpes simplex virus type 2 (HSV-2) is transmitted sexually and is the main cause of the condition known as genital herpes.


http://www.herpes.com/hsv1-2.html
The primary difference between the two viral types is in where they typically establish latency in the body- their "site of preference." HSV-1 usually establishes latency in the trigeminal ganglion, a collection of nerve cells near the ear. From there, it tends to recur on the lower lip or face. HSV-2 usually sets up residence in the sacral ganglion at the base of the spine. From there, it recurs in the genital area .


http://kidshealth.org/teen/your_body/skin_stuff/cold_so...
HSV-1 is very common if you have it, chances are you picked it up when you were a kid. Most people who are infected with the herpes simplex virus got it during their preschool years, most likely from close contact with someone who has it or getting kissed by an adult with the virus.

http://www.herpesguide.ca/facts/hsv_1_infections.html
Most primary infections with HSV-1 are asymptomatic. However, primary infection can cause a variety of clinical symptoms such as infection of the mouth and gums (gingivostomatitis) and a sore throat (pharyngitis) in children. Lesions may occur anywhere in the oral region and may involve the roof and floor of the mouth, as well as the inside of the cheek (the buccal mucosa). Disease may develop over a few days and can be painful. The child will often be cranky and irritable, be unwilling to eat, drink, and swallow and may also have swollen lymph nodes and fever. Sometimes these children become so dehydrated that they require hospitalization. In adolescents and adults, primary HSV-1 infection may present as tonsillitis. The tonsils may be tender and covered with a whitish substance, resembling a strep throat. The swelling and tenderness of the tonsils may result in swallowing difficulties. Sometimes blisters may also be present in the mouth. In people with normal immunity (immunocompetent) the fever will cease and lesions will heal and crust over in a week. Even when no clinical symptoms of primary HSV-1 infection are apparent, some people will shed virus making them infectious.
The skin.

HSV-1 can also infect skin, but only if the skin is damaged, such as in patients with eczema (atopics). In rare instances, primary HSV-1 infection may become wide-spread in many areas of eczema across the body (eczema herpeticum). This condition requires antiviral treatment to limit its proliferation. Children who are thumb-sucking may develop herpes on their finger. Healthcare workers, such as anesthesiologists and dentists, may also infect their fingers (digits) from patients with cold sores or oral viral shedding. Herpes infection of the finger is called herpetic whitlow. In the immunocompetent patient, most skin lesions will heal within a few weeks, unless there is a complication with a bacterial infection such as Staphylococcus aureus or Group A Streptococcus, which may require antibiotic treatment.

Primary HSV-1 infection has also been associated with a variety of other skin disorders, such as erythema multiforme and Stevens-Johnson syndrome. These conditions are not thought to be directly caused by the virus, but result from an immunological reaction in the skin at the time of infection.
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xchrom Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Dec-11-08 12:51 AM
Response to Reply #1
14. ignorant -- too bad that stupid comment won't get you a pizza -- it should. nt
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Royal Oak Rog Donating Member (506 posts) Send PM | Profile | Ignore Mon Dec-08-08 05:47 PM
Response to Original message
4. Oh just smoke a little reefer
and you'll be fine, at least that's what all the evidence seems to be pointing toward!

http://www.democraticunderground.com/discuss/duboard.ph...
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Royal Oak Rog Donating Member (506 posts) Send PM | Profile | Ignore Mon Dec-08-08 05:50 PM
Response to Reply #4
5. also
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navarth Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Dec-08-08 05:50 PM
Response to Reply #4
6. well that would keep me safe, but as for my Mom...
I doubt if I could get her to imbibe..but if I though it would help, I'd DAMN sure try
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navarth Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Dec-08-08 05:52 PM
Response to Reply #4
7. followed that link, Rog, the page ain't there no more dammit
I would really like to see that one
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Royal Oak Rog Donating Member (506 posts) Send PM | Profile | Ignore Mon Dec-08-08 06:05 PM
Response to Reply #7
9. pretty sure this was
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navarth Donating Member (1000+ posts) Send PM | Profile | Ignore Mon Dec-08-08 06:28 PM
Response to Reply #9
10. cool, thanks.
see you in RO sometime
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Royal Oak Rog Donating Member (506 posts) Send PM | Profile | Ignore Mon Dec-08-08 07:01 PM
Response to Reply #10
11. If you see a guy
with a Che' Guevara shirt on at Caribou coffee on 4th & Main that's me.
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