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Did Ibuprofen help alzheimer's patient?

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miles 2 go Donating Member (368 posts) Send PM | Profile | Ignore Thu Aug-21-08 12:43 AM
Original message
Did Ibuprofen help alzheimer's patient?
I take care of my mom. She's pretty advanced Alzheimer's to the point of having to be bed, totally incontinent, can only walk a bit with someone.

Well, mom has been getting worse, to where I am having to spoon feed her more often than she will take the bowl and spoon and feed herself. She falls asleep much throughout the day.

I gave her Ibuprofen because I thought if I ached so much at 50, then shep must have aches at 75.

After a few days on this me and my husband both noticed a big improvement in her. She's awake and alert much more of the day, and tries to feed herself much more frequently than not.

One day she was sluggish and we came to realize that she had not had the ibuprofen that morning. We gave her some and she perked right up.

Some of these results may be because she was in pain and the pain med just made her feel better, but it sure looks like it's more than that. It's much more effective than the nemenda that she takes.

I'd like to know if anyone else has similar results
Do you have someone like her in your care? or know someone who does? I'd sure like to know if anyone else has these type of results.

It's not going to work if your Alzheimer's person is still up and running around on their own, (no doubt trying to escape to that childhood home) I don't think. Though I will be interested in anyones observations.

I'm going to be posting this a few times to get anyones attention so sorry about that in advance.
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Fridays Child Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Aug-21-08 01:10 AM
Response to Original message
1. Interesting article...
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miles 2 go Donating Member (368 posts) Send PM | Profile | Ignore Thu Aug-21-08 01:16 AM
Response to Reply #1
2. thanks
I will take a look at that.
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WillYourVoteBCounted Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Aug-21-08 01:51 AM
Response to Original message
3. sleep as an escape from pain
Edited on Thu Aug-21-08 01:54 AM by WillYourVoteBCounted
It sounds like you do have miles to go. I am lucky, my mother has dementia but not Alzheimer's.
And she can feed herself and go to the bathroom, with the help of a walker.

To give you an idea of her mental capacity, she does not know what day it is or what my name is.
Heck, she might not even know her own name.

But she has chronic pain caused by arthritus in the spine and also a bad hip (replaced but a year later pain was back).

Anyway, periodically she has been incontinent (fully), and it seemed to be caused by a decrease in tolerance for some of her medicines. The meds had started to make her sleep so soundly that she didn't wake up in time to go to the bathroom in the morning. We cut back some of the meds slightly, eliminated another, and she was normal again. That and stool softeners regularly helps, plus paper pants just in case.

But if the mental functioning isnt there, then perhaps you have to live with the incontenance.

But it sounds like you definitely are on to something, and I might try adding some ibuprophrin once a day to see if I notice a change in my mother, it would be nice if she would interact more with me and my daughter.

You sound like a very kind and loving daughter, and your Mom senses that no matter how far gone she may seem or get.

Good luck.
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LeftishBrit Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Aug-21-08 02:37 AM
Response to Original message
4. There arestudies that suggest that Ibuprofen might reduce the risk of getting Alzheimers,
Edited on Thu Aug-21-08 02:38 AM by LeftishBrit
or delay its onset.

http://www.medscape.com/viewarticle/574190

I don't know of studies of its use in *treating* Alzheimers; but I would certainly discuss this with your doctor!

Wishing you and your mother all the best.

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Celebration Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Aug-21-08 07:13 AM
Response to Original message
5. Very cool
It's a Cox 2 inhibitor and I have read that some people do respond to it. The stronger ones have cardiovascular events associated with them, which is why you don't read about it all that much. I am not at all surprised that it works better than the medication--those seem to just barely work, and not even that in all most patients.

Here is some interesting information on Vitamin D and Alzheimer's--

http://www.jsonline.com/story/index.aspx?id=566695
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miles 2 go Donating Member (368 posts) Send PM | Profile | Ignore Thu Aug-21-08 11:18 AM
Response to Reply #5
6. will be checking that out
I've been hearing a lot about vitamin D. I think on here. I think I am going to increase my own milk consumption and see about a supplement. I hurt all over, all the time. I hadn't thought about it with alzheimers but will check this out.

thanks again
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Warpy Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Aug-21-08 11:44 AM
Response to Original message
7. Taking care of her pain certainly didn't hurt
and was the thing I concentrated on with my own mother, although her dementia was due more to sensory deprivation than any disease process. She, too, tended to perk up a little with her pain under control, although I had a pitched battle with her doctor to get it for her.

That she's a little more alert is no surprise, whatsoever.

The daily ibuprofen won't hurt her as long as you give it with food. If you're seeing a dramatic improvement, then you're probably treating pain she is incapable of telling you about.

As for the wandering, Alzheimer's patients do that to deal with stress. The best way to deal with it is to provide them with a place to wander, like a fenced yard with a padlocked gate.

Kudos to you for still being able to care for your mother now that she's incontinent. Incontinence is the biggest predictor of having a family member go to a nursing home. Most families will deal with everything but that.
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Cleita Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Aug-21-08 01:28 PM
Response to Original message
8. If it does, I'm taking it.
I've been diagnosed as pre-Alzheimers and have been given Namenda but I'm finding it too expensive these days with the rise in cost of gas, food and everything else squeezing me and have been looking for an alternative a cheaper one.
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MannyGoldstein Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Aug-21-08 05:49 PM
Response to Reply #8
9. Ibuprofen, Fish Oil, And Alpha Lipoic Acid
All seem to be linked to lower incidence of AD.

There's recently been some amazing results found with Methylene Blue - a cheap and common drug that's been used for a long, long time to treat other things: http://www.sciencedaily.com/releases/2008/08/0808181013...

Good luck!
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