Democratic Underground Latest Greatest Lobby Journals Search Options Help Login
Google

Researchers Design Alzheimer’s Antibodies

Printer-friendly format Printer-friendly format
Printer-friendly format Email this thread to a friend
Printer-friendly format Bookmark this thread
Home » Discuss » Topic Forums » Health Donate to DU
 
OKIsItJustMe Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Dec-09-11 05:49 PM
Original message
Researchers Design Alzheimer’s Antibodies
http://news.rpi.edu/update.do?artcenterkey=2959

Researchers Design Alzheimer’s Antibodies

A Surprisingly Simple Method To Target Harmful Proteins

Researchers at Rensselaer Polytechnic Institute have developed a new method to design antibodies aimed at combating disease. The surprisingly simple process was used to make antibodies that neutralize the harmful protein particles that lead to Alzheimer’s disease.

The process is reported in the Dec. 5 Early Edition of the journal Proceedings of the National Academy of Sciences (PNAS). The process, outlined in the paper, titled “Structure-based design of conformation- and sequence-specific antibodies against amyloid β,” could be used as a tool to understand complex disease pathology and develop new antibody-based drugs in the future.



Scientists have long sought methods for designing antibodies to combat specific ailments. However, the incredible complexity of designing antibodies that only attached to a target molecule of interest has prevented scientists from realizing this ambitious goal.



Alzheimer’s disease is due to a specific protein – the Alzheimer’s protein – sticking together to form protein particles. These particles then damage the normal, healthy functions of the brain. The formation of similar toxic protein particles is central to diseases such as Parkinson’s and mad cow disease.

Refresh | +12 Recommendations Printer Friendly | Permalink | Reply | Top
virgogal Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Dec-09-11 05:52 PM
Response to Original message
1. What a miracle a cure for that horrendous disease would be.
Printer Friendly | Permalink | Reply | Top
 
mzmolly Donating Member (1000+ posts) Send PM | Profile | Ignore Fri Dec-09-11 09:21 PM
Response to Original message
2. Fascinating.
I hope this leads to a progress.
Printer Friendly | Permalink | Reply | Top
 
Duer 157099 Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Dec-13-11 01:52 PM
Response to Original message
3. Cannot find this article
I mean the actual PNAS one :shrug:
Printer Friendly | Permalink | Reply | Top
 
DU AdBot (1000+ posts) Click to send private message to this author Click to view 
this author's profile Click to add 
this author to your buddy list Click to add 
this author to your Ignore list Sun Sep 21st 2014, 12:33 AM
Response to Original message
Advertisements [?]
 Top

Home » Discuss » Topic Forums » Health Donate to DU

Powered by DCForum+ Version 1.1 Copyright 1997-2002 DCScripts.com
Software has been extensively modified by the DU administrators


Important Notices: By participating on this discussion board, visitors agree to abide by the rules outlined on our Rules page. Messages posted on the Democratic Underground Discussion Forums are the opinions of the individuals who post them, and do not necessarily represent the opinions of Democratic Underground, LLC.

Home  |  Discussion Forums  |  Journals |  Store  |  Donate

About DU  |  Contact Us  |  Privacy Policy

Got a message for Democratic Underground? Click here to send us a message.

© 2001 - 2011 Democratic Underground, LLC