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Guardian UK: Doped and duped

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marmar Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Aug-08-09 09:53 AM
Original message
Guardian UK: Doped and duped
Doped and duped
Adverse effects of widely-prescribed drugs are often overlooked because there is so little truly independent academic evidence

David Healy
guardian.co.uk, Saturday 8 August 2009


Since 2005, the SSRI paroxetine, first marketed by GlaxoSmithKline as Seroxat, has carried warnings of risk of birth defects. In the US litigation in which I have been asked to give evidence, the plaintives will argue that, even before they were launched, there was good laboratory evidence that the SSRIs might cause problems, and, following their initial marketing, evidence emerged over a decade ago from clinical use that the drugs actually do cause problems.

Yet these drugs have been actively promoted, de facto primarily to women of child-bearing years. How could this happen?

Part of the problem is that having gone to their GP with a nervous problem, many women become dependent on a prescribed SSRI and find it impossible to stop using it whether they wish to get pregnant or if they find they are pregnant while on treatment. But few, if any, of these women will have been informed of either the risk of birth defects or the risk of becoming addicted. Why not?

What we are seeing here is the astonishing marketing power of pharmaceutical companies, which can now effect huge changes in medical culture within months. In this case, a great part of the scientific literature (the primary marketing tool of companies) on the use of antidepressants in pregnancy and on dependence on antidepressants is ghostwritten just as virtually all literature on giving antidepressants to children was, at one point, company-written. Firms of medical writers are contracted to pharmaceutical companies to place in academic journals articles attributed to, but not actually authored by, university researchers. ...........(more)

The complete piece is at: http://www.guardian.co.uk/commentisfree/2009/aug/08/ser...




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Voice for Peace Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Aug-08-09 10:05 AM
Response to Original message
1. common sense says
the pharmaceutical companies use human beings as their guinea pigs for experimentation and corporate profit.
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marmar Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Aug-08-09 04:56 PM
Response to Reply #1
2. Very true.
n/t
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bemildred Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Aug-08-09 05:30 PM
Response to Original message
3. One can maximize profit or quality of care, but not both.
Edited on Sat Aug-08-09 05:31 PM by bemildred
Quality care costs, and the only way to maximize profit beyond a certain point, is to reduce cost, i.e. quality.
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