Mutated gene raises autism risk, study finds

[mzteris]

WASHINGTON (Reuters) -- U.S. researchers said Monday that they had identified a genetic mutation that raises the risk of autism and could also explain some of the other symptoms seen in children with autism.

Although autism and similar disorders can clearly run in families, theirs is the first study to find a definitive genetic link to the disorder, which affects as many as 1 in 175 U.S. children.

Dr. Pat Levitt and colleagues at Vanderbilt University in Nashville, Tennessee, studied 743 families in which 1,200 family members were affected by autism spectrum disorders, which range from fully disabling autism to Asperger's syndrome.

They found a single mutation in a gene called MET, which is known to be involved in brain development, regulation of the immune system and repair of the gastrointestinal system. All of these systems can be affected in children with autism.

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http://www.cnn.com/2006/HEALTH/10/16/autism.genes.reut/index.html