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Reply #7: Circumcision May Reduce Incidence of HIV, HSV-2, HPV Infection [View All]

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denem Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Mar-26-09 03:48 PM
Response to Original message
7. Circumcision May Reduce Incidence of HIV, HSV-2, HPV Infection
Edited on Thu Mar-26-09 02:49 PM by denem
Source: Medscape

March 25, 2009 Male circumcision significantly reduced the incidence of HIV and herpes simplex virus type 2 (HSV-2) infection and the prevalence of human papillomavirus (HPV) infection, suggesting potential public health benefits, according to the results of a randomized controlled trial reported in the March 26 issue of the New England Journal of Medicine.

"Male circumcision significantly reduced the incidence of...HIV infection among men in three clinical trials," write Aaron A.R. Tobian, MD, PhD, from Bloomberg School of Public Health, Johns Hopkins University in Baltimore, Maryland, and colleagues. "We assessed the efficacy of male circumcision for the prevention of...HSV-2 and...HPV infections and syphilis in HIV-negative adolescent boys and men."

Two trials of male circumcision to prevent HIV and other sexually transmitted infections in a rural Ugandan population enrolled a total of 5534 HIV-negative, uncircumcised male subjects aged 15 to 49 years. Of 3393 subjects (61.3%) who were HSV-2 seronegative at enrollment, 1684 had been randomly assigned to undergo immediate circumcision (intervention group) and 1709 to undergo circumcision after 24 months (control group). Subjects were tested for HSV-2 and HIV infection and syphilis and underwent physical examinations and interviews at baseline and at 6, 12, and 24 months. A subgroup of subjects was also evaluated for HPV infection at baseline and at 24 months.

Read more:

The incidence of infection for HIV, HSV-2 and HPV was 'cut' by about a third in the circumcised males, or put another way, uncircumcised males are 50% more likely (as a population) to carry these STDs.
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  -STDs May Change Stance on Circumcision Coventina  Mar-26-09 09:44 AM   #0 
  - Ah...a circumcision thread. Hold on...  MineralMan   Mar-26-09 10:09 AM   #1 
  - ...  xchrom   Mar-26-09 11:06 AM   #2 
  - LOL  subterranean   Mar-26-09 11:15 AM   #4 
  - More scare tactics  subterranean   Mar-26-09 11:14 AM   #3 
  - This study just seems weird  semillama   Mar-26-09 01:44 PM   #5 
  - not again  ml66uk   Mar-26-09 03:26 PM   #6 
  - Circumcision May Reduce Incidence of HIV, HSV-2, HPV Infection  denem   Mar-26-09 03:48 PM   #7 
     - Grabbing the popcorn  FLAprogressive   Mar-26-09 03:48 PM   #8 
     - beat me to it!  county worker   Mar-26-09 03:48 PM   #11 
     - gimme gimme gimme  Javaman   Mar-26-09 03:48 PM   #23 
     - Wait till I get my popcorn will you?  county worker   Mar-26-09 03:48 PM   #9 
     - Share some, plz  Sultana   Mar-26-09 03:48 PM   #28 
     - Males should have the choice to have, or not have, this procedure done. nt  ZombieHorde   Mar-26-09 03:48 PM   #10 
     - And women should have the choice to turn up their noses at men  kestrel91316   Mar-26-09 03:48 PM   #13 
     - No one should sleep with someone they don't trust, regardless of their body modifications. nt  ZombieHorde   Mar-26-09 03:48 PM   #15 
     - And men have the right to turn up their noses at women with small breasts.  Crunchy Frog   Mar-26-09 03:51 PM   #32 
     - Well, since the procedure is least traumatic for infants  Warpy   Mar-26-09 03:48 PM   #19 
        - "least traumatic for infants"  ZombieHorde   Mar-26-09 03:48 PM   #22 
           - Cephalocaudal myelin sheath development  Warpy   Mar-26-09 04:28 PM   #35 
           - I think your information may be a little out of date.  Crunchy Frog   Mar-26-09 05:07 PM   #36 
              - That only says they can feel pain, which is true  Warpy   Mar-26-09 06:40 PM   #39 
              - Could you point me to relevant medical literature  Crunchy Frog   Mar-26-09 07:18 PM   #40 
                 - Any good child development textbook will tell you all about it.  Warpy   Mar-26-09 07:21 PM   #41 
                    - Could you point me to one please?  Crunchy Frog   Mar-26-09 07:34 PM   #42 
              - From the first link...  ZombieHorde   Mar-26-09 11:59 PM   #45 
           - Perhaps least *lastingly* traumatic for infants  Orrex   Mar-26-09 06:12 PM   #37 
     - Old news.  kestrel91316   Mar-26-09 03:48 PM   #12 
     - Haven't we always known this.  DURHAM D   Mar-26-09 03:48 PM   #14 
     - Damn!  Cronus Protagonist   Mar-26-09 03:48 PM   #16 
     - We didn't have our sons cut.  Kceres   Mar-26-09 03:48 PM   #17 
     - I'm with you  cullen2382   Mar-26-09 03:48 PM   #18 
     - Don't forget the often overlooked Muslim population  marshall   Mar-26-09 04:17 PM   #34 
     - it is more difficult as an adult . . .  DollyM   Mar-26-09 03:48 PM   #20 
     - I know. We took that into consideration.  Kceres   Mar-26-09 03:48 PM   #29 
     - I had twin boys eight weeks ago. I didn't have them cut either.  Crunchy Frog   Mar-26-09 03:55 PM   #33 
     - Cool! You should offer them the same choice about vaccination and whether to cut the umbilical cord.  Orrex   Mar-26-09 06:18 PM   #38 
        - My son seemed more upset by his vaccinations so far than the circumcision  Nikia   Mar-26-09 07:46 PM   #43 
           - Curiously, my five year old hardly bats an eye about vaccinations  Orrex   Mar-26-09 08:19 PM   #44 
     - Why does this topic keep popping up at DU?  subterranean   Mar-26-09 03:48 PM   #21 
     - Because it involves the penis. They always...pop up! LOL  Javaman   Mar-26-09 03:48 PM   #24 
     - It's weird.  The Stranger   Mar-26-09 03:48 PM   #25 
     - i suspect one or two individuals are propagating it  erebusman   Mar-26-09 03:48 PM   #27 
     - Well, duh, scar tissue is much harder to get through for pathogens than a mucus membrane  aldo   Mar-26-09 03:48 PM   #26 
     - In Uganda...a New Zealand study shows a different outcome.  Crunchy Frog   Mar-26-09 03:48 PM   #30 
     - Mutilation May Reduce Incidence of HIV, HSV-2, HPV Infection  percussivemadness   Mar-26-09 03:48 PM   #31 

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