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Reply #5: That may be because statins like Lipitor cause coq10 deficiencies [View All]

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gulfcoastliberal Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Aug-03-06 07:21 PM
Response to Reply #2
5. That may be because statins like Lipitor cause coq10 deficiencies
Via inhibiting coq10 biosynthesis:

High Cholesterol

Levels of CoQ10 tend to be lower in people with high cholesterol compared to healthy individuals of the same age. In addition, certain cholesterol-lowering drugs called statins (such as atorvastatin, cerivastatin, lovastatin, pravastatin, simvastatin) appear to deplete natural levels of CoQ10 in the body. Taking CoQ10 supplements can correct the deficiency caused by statin medications without affecting the medication's positive effects on cholesterol levels.


Other
Medications that can lower the levels of coenzyme Q10 in the body include statins for cholesterol (atorvastatin, cerivastatin, lovastatin, pravastatin, simvastatin), fibric acid derivatives for cholesterol (specifically, gemfibrozil), beta-blockers for high blood pressure (such as atenolol, labetolol, metoprolol, and propranolol), and tricyclic antidepressant medications (including amitriptyline, amoxapine, clomipramine, desipramine, doxepin, imipramine, nortriptyline, protriptyline, and trimipramine).


http://www.umm.edu/altmed/ConsSupplements/CoenzymeQ10cs.html
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