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AnotherDreamWeaver

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Member since: Fri Nov 17, 2006, 01:37 AM
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Regulators Discover a Hidden Viral Gene in Commercial GMO Crops

Regulators Discover a Hidden Viral Gene in Commercial GMO Crops
JONATHAN LATHAM and ALLISON WILSON - Independent Science News


Click through to see the charts.
(Here is the link "click through") http://independentsciencenews.org/commentaries/regulators-discover-a-hidden-viral-gene-in-commercial-gmo-crops/
(It is also the link the title at the bottom should take you to.)

How should a regulatory agency announce they have discovered something potentially very important about the safety of products they have been approving for over twenty years?

In the course of analysis to identify potential allergens in GMO crops, the European Food Safety Authority (EFSA) has belatedly discovered that the most common genetic regulatory sequence in commercial GMOs also encodes a significant fragment of a viral gene (Podevin and du Jardin 2012). This finding has serious ramifications for crop biotechnology and its regulation, but possibly even greater ones for consumers and farmers. This is because there are clear indications that this viral gene (called Gene VI) might not be safe for human consumption. It also may disturb the normal functioning of crops, including their natural pest resistance.

What Podevin and du Jardin discovered is that of the 86 different transgenic events (unique insertions of foreign DNA) commercialized to-date in the United States 54 contain portions of Gene VI within them. They include any with a widely used gene regulatory sequence called the CaMV 35S promoter (from the cauliflower mosaic virus; CaMV). Among the affected transgenic events are some of the most widely grown GMOs, including Roundup Ready soybeans (40-3-2) and MON810 maize. They include the controversial NK603 maize recently reported as causing tumors in rats (Seralini et al. 2012).

The researchers themselves concluded that the presence of segments of Gene VI 'might result in unintended phenotypic changes”. They reached this conclusion because similar fragments of Gene VI have already been shown to be active on their own (e.g. De Tapia et al. 1993). In other words, the EFSA researchers were unable to rule out a hazard to public health or the environment.




In general, viral genes expressed in plants raise both agronomic and human health concerns (reviewed in Latham and Wilson 2008). This is because many viral genes function to disable their host in order to facilitate pathogen invasion. Often, this is achieved by incapacitating specific anti-pathogen defenses. Incorporating such genes could clearly lead to undesirable and unexpected outcomes in agriculture. Furthermore, viruses that infect plants are often not that different from viruses that infect humans. For example, sometimes the genes of human and plant viruses are interchangeable, while on other occasions inserting plant viral fragments as transgenes has caused the genetically altered plant to become susceptible to an animal virus (Dasgupta et al. 2001). Thus, in various ways, inserting viral genes accidentally into crop plants and the food supply confers a significant potential for harm.

The Choices for Regulators

The original discovery by Podevin and du Jardin (at EFSA) of Gene VI in commercial GMO crops must have presented regulators with sharply divergent procedural alternatives. They could 1) recall all CaMV Gene VI-containing crops (in Europe that would mean revoking importation and planting approvals) or, 2) undertake a retrospective risk assessment of the CaMV promoter and its Gene VI sequences and hope to give it a clean bill of health.

It is easy to see the attraction for EFSA of option two. Recall would be a massive political and financial decision and would also be a huge embarrassment to the regulators themselves. It would leave very few GMO crops on the market and might even mean the end of crop biotechnology.

Regulators, in principle at least, also have a third option to gauge the seriousness of any potential GMO hazard. GMO monitoring, which is required by EU regulations, ought to allow them to find out if deaths, illnesses, or crop failures have been reported by farmers or health officials and can be correlated with the Gene VI sequence. Unfortunately, this particular avenue of enquiry is a scientific dead end. Not one country has carried through on promises to officially and scientifically monitor any hazardous consequences of GMOs (1).

Unsurprisingly, EFSA chose option two. However, their investigation resulted only in the vague and unreassuring conclusion that Gene VI 'might result in unintended phenotypic changes” (Podevin and du Jardin 2012). This means literally, that changes of an unknown number, nature, or magnitude may (or may not) occur. It falls well short of the solid scientific reassurance of public safety needed to explain why EFSA has not ordered a recall.

Can the presence of a fragment of virus DNA really be that significant? Below is an independent analysis of Gene VI and its known properties and their safety implications. This analysis clearly illustrates the regulators’ dilemma.

The Many Functions of Gene VI

To read the rest of this article:
Regulators Discover a Hidden Viral Gene in Commercial GMO Crops

(This came to me in an email, I don't see 'hot links' coming through however...?)
Posted by AnotherDreamWeaver | Wed Jan 23, 2013, 12:02 PM (1 replies)

How many Cars in Russia have a Camera? 13 min video of bad driving...

Here: http://thebrowser.com/videos/driving-russia?utm_source=The+Browser's+mailing+list&utm_campaign=86fc59d2af-Newsletter&utm_medium=email

How did they collect so many clips?

(A search of driving in Russia didn't show any posts earlier...)
Posted by AnotherDreamWeaver | Mon Dec 10, 2012, 01:30 AM (5 replies)

Went to the fire dept. meeting tonight and someone brought a clipping from the paper,

I found out the neighborhood has been upgrading:
http://www.pressdemocrat.com/article/20121102/LIFESTYLE/121109968

A wine tasting room went in on Myers Grade last summer.

(almost embarrassed to talk something besides election politics...)
Posted by AnotherDreamWeaver | Tue Nov 6, 2012, 02:33 AM (1 replies)

Three Activists against the banks, from the Thrive movement

I see that the video they put out over a year ago had some threads, but I didn't see this new article: http://www.thrivemovement.com/bold-actiivists-reveal-strategies-for-fighting-home-foreclosures-and-balancing-government-budget.blog

(I can't say I support the third guy, but I'm not in that position either.) I feel inspired by the actions of the first two.
Posted by AnotherDreamWeaver | Thu Oct 18, 2012, 12:58 AM (0 replies)

Yes on California Prop 37

Listening to 'Your Own Health and Fitness' on KPFA.org today I learned of this movie "Genetic Roulette." See: http://responsibletechnology.org/

"Are you and your family on the wrong side of a bet?

When the US government ignored repeated warnings by its own scientists and allowed untested genetically modified (GM) crops into our environment and food supply, it was a gamble of unprecedented proportions. The health of all living things and all future generations were put at risk by an infant technology.

After two decades, physicians and scientists have uncovered a grave trend. The same serious health problems found in lab animals, livestock, and pets that have been fed GM foods are now on the rise in the US population. And when people and animals stop eating genetically modified organisms (GMOs), their health improves."
Posted by AnotherDreamWeaver | Tue Oct 16, 2012, 05:32 PM (4 replies)

They are genetically engineering the American Chestnut...

The American Chestnut Foundation has been working for years to breed blight resistance into the American Chestnut by crossing and back crossing Asian breeds. (Japanese, Chinese and Korean varieties.) This article isn't the best (96 and 6 are not 100) and disturbs me about GM work.
http://www.the-scientist.com/?articles.view/articleNo/32743/title/American-Chestnut-to-Rise-Again/

Posted by AnotherDreamWeaver | Mon Oct 8, 2012, 03:39 PM (98 replies)

Was there a magic jump into DU-4 this morning?

I'm still logged in from yesterday, but the "Greatest Threads" page no longer is a colum on the right of most recommended and one on the left of just getting 5 recommendations. There are only the most recommended in the last 24 hours.

Thanks,
ADW
Posted by AnotherDreamWeaver | Mon Sep 24, 2012, 02:53 PM (4 replies)

Have a good "Billy Sipple Day" along with the Equinox

http://www.huffingtonpost.com/2011/09/22/billy-sipple-day-san-francisco_n_977000.html

Just want to remember the man,
ADW
Posted by AnotherDreamWeaver | Sat Sep 22, 2012, 11:45 AM (2 replies)

On the fall of capitalism, from counter-punch

http://www.counterpunch.org/2012/09/20/the-waning-of-the-modern-ages/

And the last paragraph:
"In a word, its number is up, and it is our fortune or misfortune, as I said before, to be living during a time of very large, and very difficult, transition. An old way of life dies, a new one eventually comes into being. Of this, the poet Mark Strand remarks: “No need to rush; the end of the world is only the end of the world as you know it.” For some odd reason, I find that thought rather comforting."

Morris Berman’s latest book is Why America Failed.
Posted by AnotherDreamWeaver | Fri Sep 21, 2012, 04:07 PM (5 replies)

I wish Elizabeth Warren spoke about Pollution of Nuclear Power

Just speaking about his support of Oil Subsidies wasn't as hard a hit as she could have had.
Posted by AnotherDreamWeaver | Thu Sep 20, 2012, 08:01 PM (5 replies)
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