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Tue Feb 12, 2013, 06:12 AM

Zinc 'keeps immune system in check'

http://www.bbc.co.uk/news/health-21372790

***SNIP

Feedback loop
Through further experiments in human cells and animal studies the researchers found that a protein called NF-kB lured zinc into the immune cells that responded fastest to fight infection.

Once inside, the zinc then put the brakes on further activity in the NF-kB pathway, slowing down the immune response and limiting the amount of inflammation, the study, in Cell Reports, indicated.

It was effectively a feedback loop, stopping the process getting out of hand, the researchers said.

Study leader, Dr Daren Knoell, said: "The immune system has to work under very strict balance, and this is a classic example of where more is not always better.

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