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Mon Oct 8, 2012, 10:36 PM

US scientists aim to make human sperm from stem cells

Source: BBC

US scientists aim to make human sperm from stem cells
By Regan Morris
BBC News, Los Angeles

Skin cells become 'grandparents'
US researchers say they will redouble their efforts to create human sperm from stem cells following the success of a Japanese study involving mice.

A Kyoto University team used mice stem cells to create eggs, which were fertilised to produce baby mice.

Dr Renee Pera, of Stanford University in California, aims to create human sperm to use for reproduction within two years, and eggs within five years.

........................

"I know people think it's Frankenstein medicine, but I think it's not an imagined or lessened health problem - infertility affects your whole life," Dr Pera says.

Read more: http://www.bbc.co.uk/news/world-us-canada-19879113

41 replies, 5966 views

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Arrow 41 replies Author Time Post
Reply US scientists aim to make human sperm from stem cells (Original post)
kpete Oct 2012 OP
Orrex Oct 2012 #1
rug Oct 2012 #2
johnlucas Oct 2012 #31
LadyHawkAZ Oct 2012 #3
WheelWalker Oct 2012 #4
LadyHawkAZ Oct 2012 #5
WheelWalker Oct 2012 #12
LadyHawkAZ Oct 2012 #15
formercia Oct 2012 #29
4th law of robotics Oct 2012 #32
dimbear Oct 2012 #6
davidpdx Oct 2012 #36
Missycim Oct 2012 #38
dimbear Oct 2012 #39
Missycim Oct 2012 #41
Speck Tater Oct 2012 #7
4th law of robotics Oct 2012 #35
Gore1FL Oct 2012 #8
jberryhill Oct 2012 #27
HeeBGBz Oct 2012 #9
defacto7 Oct 2012 #10
jmowreader Oct 2012 #11
midnight Oct 2012 #13
JRLeft Oct 2012 #14
Fearless Oct 2012 #19
AAO Oct 2012 #16
yurbud Oct 2012 #17
Downwinder Oct 2012 #18
PD Turk Oct 2012 #20
lumpy Oct 2012 #21
truthisfreedom Oct 2012 #22
Socal31 Oct 2012 #23
Tcbys Oct 2012 #24
Alcibiades Oct 2012 #34
Nihil Oct 2012 #25
4th law of robotics Oct 2012 #33
Nihil Oct 2012 #37
polichick Oct 2012 #26
RKP5637 Oct 2012 #28
RC Oct 2012 #30
lunatica Oct 2012 #40

Response to kpete (Original post)

Mon Oct 8, 2012, 10:39 PM

1. Thank God somebody's working to address the world's sperm shortage

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Response to kpete (Original post)

Mon Oct 8, 2012, 10:46 PM

2. Scientists bleed life of its simple pleasures.

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Response to rug (Reply #2)

Tue Oct 9, 2012, 09:43 AM

31. Yeah I know right!

Take ALL the fun out of sex why don't you?

Just fix sexual malfunctions. Don't play God around here.
John Lucas

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Response to kpete (Original post)

Mon Oct 8, 2012, 10:51 PM

3. What on earth for?

Was there a sperm shortage that I was previously unaware of?

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Response to LadyHawkAZ (Reply #3)

Mon Oct 8, 2012, 10:56 PM

4. There are reports, largely localized.

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Response to WheelWalker (Reply #4)

Mon Oct 8, 2012, 11:06 PM

5. I have conducted my own independent studies locally

and concluded that the men here are having no problems.



Seriously, this just seems weird. Was there a genuine need for this, other than individual vanity? The human race as a whole seems to be reproducing just fine.

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Response to LadyHawkAZ (Reply #5)

Mon Oct 8, 2012, 11:52 PM

12. Truly. I couldn't agree more. Now if they found a way to frustrate the little buggers

that gave us an effective male contraceptive...

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Response to WheelWalker (Reply #12)

Tue Oct 9, 2012, 12:15 AM

15. r'Amen! n/t

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Response to LadyHawkAZ (Reply #3)

Tue Oct 9, 2012, 08:06 AM

29. The perfect Soldier

Cloning the ultimate Warrior of the 21st Century.

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Response to LadyHawkAZ (Reply #3)

Tue Oct 9, 2012, 09:47 AM

32. For individuals with fertility problems, yes.

 

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Response to kpete (Original post)

Mon Oct 8, 2012, 11:10 PM

6. This is the only practical way to develop societies of just one sex. Some kinks to work out on the

male pregnancies.

Cloning is so boring after the thrill wears off.

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Response to dimbear (Reply #6)

Tue Oct 9, 2012, 10:09 AM

36. I'm not so sure us guys could handle that much pain

we are big babies. lol

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Response to davidpdx (Reply #36)

Tue Oct 9, 2012, 12:08 PM

38. Please its been told that passing a kidney stone

 

is a lot worse then giving birth. I can attest the stone part is painful

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Response to Missycim (Reply #38)

Tue Oct 9, 2012, 05:38 PM

39. There's been some research into having other animals, such as cows, gestate humans.

That might be a good avenue for the guys only section.

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Response to dimbear (Reply #39)

Tue Oct 9, 2012, 05:53 PM

41. thats disgusting

 

I hope I'm out of here before that day

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Response to kpete (Original post)

Mon Oct 8, 2012, 11:13 PM

7. Another advance in the women's war on men

 

Clearly once they can reproduce without us men they will simply haul us all away to those secret clinics in the mountains and subject us all to mandatory sex-change operations.


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Response to Speck Tater (Reply #7)

Tue Oct 9, 2012, 10:01 AM

35. Women are becoming obsolete too:

 

http://online.wsj.com/article/SB10000872396390443768804578036580428448760.html?mod=WSJ_hpp_sections_health

So . . . I maybe we'll split in to two warring factions.

I remember some late night post-apocalyptic movie on that theme. Can't recall the name though.

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Response to kpete (Original post)

Mon Oct 8, 2012, 11:16 PM

8. I can make it cheaper.

I will be happy to demonstrate for investors.

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Response to Gore1FL (Reply #8)

Tue Oct 9, 2012, 07:56 AM

27. You wouldn't be jerking us around would you?

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Response to kpete (Original post)

Mon Oct 8, 2012, 11:25 PM

9. Creepy

Something bad waiting to happen.

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Response to kpete (Original post)

Mon Oct 8, 2012, 11:33 PM

10. So what do they think they are going to get

when they cross those Japanese stem cell mice eggs with those Stanford stem cell human sperms?

I just don't get it!




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Response to kpete (Original post)

Mon Oct 8, 2012, 11:50 PM

11. There's a slogan "all gave some, some gave all" that comes to mind

It refers to people who have gone to war.

In Bush's illegal wars, there were two signature injuries: traumatic brain injury and genital damage. We ran a story several months back about soldiers coming back with their balls blown off who were super depressed they'd never be fathers.

The obvious solution is to quit sending guys to illegal wars where you can get your balls blown off, but that doesn't do much for the thousands of troops it already happened to.

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Response to kpete (Original post)

Mon Oct 8, 2012, 11:58 PM

13. Last year Gov. Perry was privileged enough to use it to enhance his health.

It was deemed to risky for the rest of us... I wonder how long the rich get access to these advances while the rest of us just read about them....

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Response to kpete (Original post)

Tue Oct 9, 2012, 12:13 AM

14. This may help transgendered people with the ability to reproduce.

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Response to JRLeft (Reply #14)

Tue Oct 9, 2012, 12:59 AM

19. Thank you!

For a reasonable response!

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Response to kpete (Original post)

Tue Oct 9, 2012, 12:22 AM

16. HOLD THE PHONE! These scientists wouldn't happen to be women? We may become expendable guys...

 

There is something seriously wrong here!!

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Response to kpete (Original post)

Tue Oct 9, 2012, 12:27 AM

17. it would be easier to harvest it from gym socks

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Response to kpete (Original post)

Tue Oct 9, 2012, 12:33 AM

18. On the bright side. If you spend too much time in front

of a radar unit, all is not lost.

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Response to kpete (Original post)

Tue Oct 9, 2012, 01:20 AM

20. oh no

are they working on "Gendercide" ?

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Response to kpete (Original post)

Tue Oct 9, 2012, 01:39 AM

21. Jesus Christ, just what we need, more sperm.

insane

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Response to kpete (Original post)

Tue Oct 9, 2012, 02:30 AM

22. Can't wait for the "playing god" claims from the religious right.

Actually, we're being human. This is what we do... we figure out what is possible and then try it.

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Response to kpete (Original post)

Tue Oct 9, 2012, 02:51 AM

23. I'm all for it.

Afterall, so many "accidental" or secondary scientific discoveries happen when we least expect it.

However, as others have mentioned in this thread, sperm is not in short supply!

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Response to kpete (Original post)

Tue Oct 9, 2012, 03:25 AM

24. The problem with that is. How does a artificial made sperm compare to natural made sperm.

 

In terms of Genetic defects. If theres no difference that maybe good way for couples to have kids.

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Response to Tcbys (Reply #24)

Tue Oct 9, 2012, 10:01 AM

34. We won't know for some time

These new reproductive techniques are an experiment in the making. We only get results as they are used on a large scale basis. We are only now, for example, finding out about the risks of the most common reproductive innovations:

http://www.nytimes.com/2012/05/15/health/research/birth-defect-risk-higher-with-fertility-treatments-study-shows.html?_r=0

One finding:

"Women who had any fertility treatment were more likely to have a stillbirth, to have a low-birthweight baby, and to deliver before 32 weeks of gestation. Unsurprisingly, parental factors played a large role. For example, babies conceived without treatment by women who had previously had fertility treatments had a 25 percent greater risk for birth defects.

Dr. Pasquale Patrizio, director of the Yale University Fertility Center, who was not involved in the study, said this was a significant finding. “The most important message that I take from this is that it confirms pretty strongly the fact that infertility itself increases the risk for birth defects. If you’re infertile, you’re already at higher risk even if you don’t take any treatment.”

That's only one possibility: the other is that things such as hormones may have longer-acting effects than we understand, and that some of the increased risk is due to the treament itself.

We'll only really know if this is successful when, in a couple of decades, the people produced by this method are examined.

Spermatogenesis itself is a complicated process not entirely understood by medical science. THere is a lot that can go wrong: while it's common to attribute birth defects to such things as the age of the mother (i.e. it seems there's an impulse to blame women) it's becoming increasingly evident that the health and enviromnent of the father is also important. There has been a very strong selection pressure that has enabled most male organisms today to get this right, and I really doubt anything coming out of the lab will be as good for a very long time.

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Response to kpete (Original post)

Tue Oct 9, 2012, 07:50 AM

25. How utterly stupid is that?

There are over 7 billion people on this planet and it is growing every day.
There is absolutely NO shortage of human sperm and definitely NO shortage
of new human mouths to feed so just WHY is this viewed as a "useful" issue
to solve?

How about solving the problem of too many unwanted children before
displacing even more children by avoiding adoption in favour of a pointless
gimmick like this?

How about solving the problem of too many inherited diseases ?

How about solving the problems of child abuse, kidnapping, murder,
exploitation rather than just providing fuel?



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Response to Nihil (Reply #25)

Tue Oct 9, 2012, 09:51 AM

33. Those are two different issues

 

one is a scientific problem.

The other is social.

How about solving the problem of too many unwanted children before
displacing even more children by avoiding adoption in favour of a pointless
gimmick like this?


How do you "solve" that problem? People aren't stray cats. You can't forcibly sterilize them or put them down if they breed out of control.


How about solving the problem of too many inherited diseases ?


By telling certain people they can't breed?

How about solving the problems of child abuse, kidnapping, murder,
exploitation rather than just providing fuel?


You know, if we got away with all medical care relating to pregnancies and childhood vaccinations there would be more children dying at a young age. That would alleviate this problem would it not?

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Response to 4th law of robotics (Reply #33)

Tue Oct 9, 2012, 11:37 AM

37. No, one is a scientific "solution" in search of a problem.

I notice you didn't address my first point
>> There are over 7 billion people on this planet and it is growing every day.
>> There is absolutely NO shortage of human sperm and definitely NO shortage
>> of new human mouths to feed so just WHY is this viewed as a "useful" issue
>> to solve?

Does this not raise any concern in you?


I agree that the true solution to the other three questions are social rather than
purely scientific. I also agree that the "social" solutions for the first two are not ones
that will be readily accepted - especially in societies where women are viewed purely
as breeding machines to be used to achieve the goal of outnumbering the "others".

(Your third "solution" wasn't worthy of the name but the answer would be - again - social
not scientific.)

Do you agree with my first point or do you believe that we need more & more humans
on the planet?

Additionally, do you believe that adding more & more humans who are otherwise
removed from the gene pool is a good thing for the species?

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Response to kpete (Original post)

Tue Oct 9, 2012, 07:54 AM

26. Because there's a shortage somewhere?

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Response to kpete (Original post)

Tue Oct 9, 2012, 08:01 AM

28. Immediately comes to my mind is WWII and Hitler wanting to create the perfect race and

Josef Mengele in his labs with horrific medical research experiments on humans.

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Response to kpete (Original post)

Tue Oct 9, 2012, 08:43 AM

30. For those people that have trouble reproducing, there is a reason for that.

 

And working around that infertility weakens the human race genetically as a whole. You know, evolution? The human race is already fucked up enough as it is.

Don't let Monsanto get involved in this. Do we really need people that make their own Round Up? Just piss into the 5 gallon can till it is full.

It is bullshit that just because we can reproduce, we should. Being pregnant is not a miracle, it is evolution, the normal course of events of being an sexual animal. We are destroying this planet, the only home we will ever know, with our shear numbers. We don't need more help to increase the population on this already over crowded planet. We are doing that through our normal arrogance just fine.
There are more kids to adopt that parents to adopt them. As others have mentioned, we need birth control for both sexes far more than we need new ways for the infertile to reproduce and contaminate the gene pool even more.

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Response to kpete (Original post)

Tue Oct 9, 2012, 05:52 PM

40. Man is becoming expendable

It used to be that as long as they had a heartbeat during sex they could procreate and then it didn't matter if they dropped dead from the joy of it, whereas women had to hang around for a few more months to have the baby, and then to feed it for awhile.

Now? Not so much.

I'm just kidding in case anyone takes this seriously. LOL!

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