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proverbialwisdom

(4,959 posts)
Mon Mar 16, 2015, 04:17 PM Mar 2015

Study links Disneyland measles outbreak to low vaccination rates

Source: BY KAREN KAPLAN, Los Angeles Times

March 16, 2015, 12:00 p.m

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Public health officials do keep track of vaccination rates. In California, for instance, the state Department of Public Health reported that 92.6% of kindergarten students had received at least two doses of the MMR vaccine in the 2014-15 school year.

So why did the study authors go to all this trouble? In an outbreak involving a major tourist destination like Disneyland, there is no single state, county or school district that can report the overall vaccination rate, the researchers wrote. As a result, mathematical modeling like this may give a clearer picture than any individual government agency.

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In California, three state legislators have introduced a bill that would make it more difficult for parents to opt out of vaccinations by claiming a personal belief exemption. The bill, SB 277, would require children to be vaccinated against measles and other infectious diseases before enrolling in California schools.

One of the sponsors of the bill is Dr. Richard Pan, a pediatrician who represents Sacramento.

Read more: http://touch.latimes.com/#section/1780/article/p2p-83069964/

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Study links Disneyland measles outbreak to low vaccination rates (Original Post) proverbialwisdom Mar 2015 OP
More context to the mathematical modeling by the team from MIT and Boston Children’s Hospital... proverbialwisdom Mar 2015 #1
CA Measles Surveillance Update on 3/20/15: For the first time... no new measles cases were added. proverbialwisdom Mar 2015 #2
Every kid should have their MMR shot. Little Tich Mar 2015 #3
Actually, the information (CDPH data) above shows that adults are the bigger problem. proverbialwisdom Mar 2015 #4
I'll take a look. nt Little Tich Mar 2015 #5

proverbialwisdom

(4,959 posts)
1. More context to the mathematical modeling by the team from MIT and Boston Children’s Hospital...
Mon Mar 16, 2015, 05:03 PM
Mar 2015

as reported today in the journal JAMA Pediatrics:

http://archpedi.jamanetwork.com/article.aspx?articleid=2203906

Research Letter | March 16, 2015
Substandard Vaccination Compliance and the 2015 Measles Outbreak
Maimuna S. Majumder, MPH1,2; Emily L. Cohn, MPH2; Sumiko R. Mekaru, DVM, PhD2; Jane E. Huston, MPH2; John S. Brownstein, PhD2,3

It's from the CDC and it's not "mathematical modeling." A bit of a different picture, IMO.

http://www.cdc.gov/mmwr/preview/mmwrhtml/mm64e0213a1.htm

Morbidity and Mortality Weekly Report (MMWR) - Measles Outbreak: CA, December 2014–February 2015
CDC Early Release
February 13, 2015 / 64(Early Release);1-2


Jennifer Zipprich, PhD1, Kathleen Winter, MPH1, Jill Hacker, PhD1, Dongxiang Xia, MD, PhD1, James Watt, MD1, Kathleen Harriman, PhD1 (Author affiliations at end of text)

On January 5, 2015, the California Department of Public Health (CDPH) was notified about a suspected measles case. The patient was a hospitalized, unvaccinated child, aged 11 years with rash onset on December 28. The only notable travel history during the exposure period was a visit to one of two adjacent Disney theme parks located in Orange County, California. On the same day, CDPH received reports of four additional suspected measles cases in California residents and two in Utah residents, all of whom reported visiting one or both Disney theme parks during December 17–20. By January 7, seven California measles cases had been confirmed, and CDPH issued a press release and an Epidemic Information Exchange (Epi-X) notification to other states regarding this outbreak. Measles transmission is ongoing (Figure).

As of February 11, a total of 125 measles cases with rash occurring during December 28, 2014–February 8, 2015, had been confirmed in U.S. residents connected with this outbreak. Of these, 110 patients were California residents. Thirty-nine (35%) of the California patients visited one or both of the two Disney theme parks during December 17–20, where they are thought to have been exposed to measles, 37 have an unknown exposure source (34%), and 34 (31%) are secondary cases. Among the 34 secondary cases, 26 were household or close contacts, and eight were exposed in a community setting. Five (5%) of the California patients reported being in one or both of the two Disney theme parks during their exposure period outside of December 17–20, but their source of infection is unknown. In addition, 15 cases linked to the two Disney theme parks have been reported in seven other states: Arizona (seven), Colorado (one), Nebraska (one), Oregon (one), Utah (three), and Washington (two), as well as linked cases reported in two neighboring countries, Mexico (one) and Canada (10).

Among the 110 California patients, 49 (45%) were unvaccinated; five (5%) had 1 dose of measles-containing vaccine, seven (6%) had 2 doses, one (1%) had 3 doses, 47 (43%) had unknown or undocumented vaccination status, and one (1%) had immunoglobulin G seropositivity documented, which indicates prior vaccination or measles infection at an undetermined time. Twelve of the unvaccinated patients were infants too young to be vaccinated. Among the 37 remaining vaccine-eligible patients, 28 (67%) were intentionally unvaccinated because of personal beliefs, and one was on an alternative plan for vaccination. Among the 28 intentionally unvaccinated patients, 18 were children (aged <18 years), and 10 were adults. Patients range in age from 6 weeks to 70 years; the median age is 22 years. Among the 84 patients with known hospitalization status, 17 (20%) were hospitalized.

The source of the initial Disney theme park exposure has not been identified. Specimens from 30 California patients were genotyped; all were measles genotype B3, which has caused a large outbreak recently in the Philippines, but has also been detected in at least 14 countries and at least six U.S. states in the last 6 months (1).

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Previously posted: http://www.democraticunderground.com/10141014872

proverbialwisdom

(4,959 posts)
2. CA Measles Surveillance Update on 3/20/15: For the first time... no new measles cases were added.
Sat Mar 21, 2015, 08:06 PM
Mar 2015
http://www.cdph.ca.gov/HEALTHINFO/DISCOND/Pages/MeaslesSurveillanceUpdates.aspx

Measles Surveillance Updates
PDF surveillance updates of measles outbreak in California. These updates will be posted every Friday.

Measles Surveillance Update 3-20-2015 (PDF) http://www.cdph.ca.gov/HealthInfo/discond/Documents/Measles_update_3_-_20_-_2015_public.pdf

Link from: http://www.ageofautism.com/2015/03/the-disneyland-measles-outbreak-is-unofficially-over.html

"For the first time since the CDPH began posting updates on-line on February 9th, no new measles cases were added to their statewide counts."
"...infectious period of the last reported case ended on March 6th."
"...the last California resident who got sick from measles caught it a month ago."

Mark Blaxill's critical examination and number-crunching of official data remains relentless. Has this CDPH Update been reported yet?

...So can we officially declare the so-called Disneyland measles outbreak over? Not so fast, says the CDPH.

“The outbreak will be considered over when 42 days have elapsed from the end of the infectious period of the last known B3 measles cases that was a not a new importation. As of today, that date will be April 17, 2015.”

So let’s do that math. If the CDPH will be ready to officially declare the outbreak finished a full 42 days after the infectious period of the last reported case ends, then that milestone (end of infectious period of the last reported case) has been passed already, fully two weeks ago on March 6th.

But the end of the infectious period is perhaps less important to specifying the final ebb of the measles outbreak than the date the last reported case became infected. The CDPH also states (see HERE) that “Infected people are usually contagious from about 4 days before their rash starts to 4 days afterwards”, so this last reported case probably saw their rash appear on March 2nd and were first infectious themselves around February 26th. As for the date of their first exposure, one analysis of the outbreak (see HERE) suggests that exposures to the measles virus occur roughly 10 days before the rash appears. That would put the date of infection of the last case around February 20th.

In other words, the last California resident who got sick from measles caught it a month ago...

GREAT NEWS! I was hoping someone would post it besides me.

Little Tich

(6,171 posts)
3. Every kid should have their MMR shot.
Sat Mar 21, 2015, 10:46 PM
Mar 2015

It really makes sense from an epidemiological point of view. I think the article proves that quite nicely.

proverbialwisdom

(4,959 posts)
4. Actually, the information (CDPH data) above shows that adults are the bigger problem.
Sun Mar 22, 2015, 01:18 AM
Mar 2015
http://www.cdph.ca.gov/HealthInfo/discond/Documents/Measles_update_3_-_20_-_2015_public.pdf

Table 3. Age distribution of confirmed measles cases

Age (years)...Total...Percent
<1...............15..........11%
1-4..............20..........15%
5-19.............24..........18%
>20..............74..........56%

Here's to transparency! And here's a wisp of a public hint that a signal for the importance of TIMING in children was observed in 2004:

http://www.morganverkamp.com/august-27-2014-press-release-statement-of-william-w-thompson-ph-d-regarding-the-2004-article-examining-the-possibility-of-a-relationship-between-mmr-vaccine-and-autism/

August 27, 2014 Press Release, “Statement of William W. Thompson, Ph.D., Regarding the 2004 Article Examining the Possibility of a Relationship Between MMR Vaccine and Autism”

FOR IMMEDIATE RELEASE - AUGUST 27,2014


STATEMENT OF WILLIAM W. THOMPSON, Ph.D., REGARDING THE 2004 ARTICLE EXAMINING THE POSSIBILITY OF A RELATIONSHIP BETWEEN MMR VACCINE AND AUTISM

My name is William Thompson. I am a Senior Scientist with the Centers for Disease Control and Prevention, where I have worked since 1998.

I regret that my coauthors and I omitted statistically significant information in our 2004 article published in the journal Pediatrics. The omitted data suggested that African American males who received the MMR vaccine before age 36 months were at increased risk for autism. Decisions were made regarding which findings to report after the data were collected, and I believe that the final study protocol was not followed.

I want to be absolutely clear that I believe vaccines have saved and continue to save countless lives. I would never suggest that any parent avoid vaccinating children of any race. Vaccines prevent serious diseases, and the risks associated with their administration are vastly outweighed by their individual and societal benefits.

My concern has been the decision to omit relevant findings in a particular study for a particular sub­ group for a particular vaccine. There have always been recognized risks for vaccination and I believe it is the responsibility of the CDC to properly convey the risks associated with receipt of those vaccines.

I have had many discussions with Dr. Brian Hooker over the last 10 months regarding studies the CDC has carried out regarding vaccines and neurodevelopmental outcomes including autism spectrum disorders. I share his belief that CDC decision-making and analyses should be transparent.

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RELATED: http://touch.orlandosentinel.com/#section/-1/article/p2p-81317483/

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