There are only two things I'm sure of about the debate, and a few guesses.
No matter what Romney will claim victory' no matter what FOX will declare Romney the winner. Those two things are certainties.
What is in question is how will the news sources respond to it. CNN will call it a tie with Romney having done a fine job, good fellow hail and hardy. CNN, or I should say Wolf Blitzer, will be disappointed in the President's performance. Rachel, Cent, Tweety, and the good Reverend will swoon. PBS/NPR will call it a tie, but hint mightily that Romney won. ABC, CBS, NBC will have irrelevant commentary for exactly 17 hours, and then they'll move on.
President Obama will win. He is the better speaker, he is much better versed in the issues, he has plans and programs to base policy, particularly economic policy, on in comparison to wild promises to be brought to fruition at some time in the future. And in the end his only written policy, the Ryan Budget, will kill Social Security and Medicaid - something you can bet will be mentioned at the debate.